5 facts about drugs to improve digestion

Overeating is not called a disease of the well-fed world for nothing. The modern lifestyle only contributes to the development of this addiction. Late dinners throughout the working week. Festive feasts with an abundance of harmful food. Family movie screenings for sandwiches and snacks. The price for the short-term pleasure of the taste buds is often unpleasant symptoms of overeating: heaviness after eating, abdominal discomfort, bloating, flatulence. And, if the body does not cope, medications to improve digestion come to the rescue. How do they work? Are they all effective? Who should take them and when?

Fact # 1. Enzymes are necessary for normal digestion

It is known that the feeling of satiety comes gradually. As the stomach is filled with food, the satiety hormone leptin begins to be produced. It affects the nerve endings in the stomach, and a signal is sent to the brain that the body is full. On average, the process takes 30 minutes1. This is enough to have time to fill your stomach with extra food.

Overload makes itself felt by a variety of sensations. We are tormented by heaviness in the stomach, bloating, general discomfort. This is due to the fact that there are not enough digestive enzymes produced by the pancreas, because the volume of food is too large.


In this case, it needs additional resources. Their function is taken over by drugs to improve digestion, or enzyme preparations. They supply the necessary supply of enzymes that process food and contribute to the proper absorption of nutrients.


Against the background of improper, irregular nutrition, more serious problems may arise. For example, heartburn, nausea, diarrhea, abdominal pain. Thus, the entire digestive system suffers.

Fact # 2. Enzymes are needed at every meal, regardless of the volume

The pancreas produces enzymes at every meal, even with a small snack. At the same time, it has its own enzyme prepared for each type of nutrient. So, lipase breaks down fats, protease helps to digest proteins, amylase converts complex carbohydrates into simple ones.

If heaviness and discomfort periodically occur after eating, this may indicate that there are not enough enzymes produced by the pancreas. There can be a lot of reasons: improper diet, fluctuations in appetite, age-related changes, hormonal failures, concomitant diseases.


That’s why the pancreas needs helpers in the form of enzyme preparations. It is important to note that they do not reduce its productivityat all 2, allowing you to process food efficiently and efficiently. And since they replace the body’s native enzymes, they should act with food as if they were produced by themselves.


 

Fact # 3. Enzymes work in the intestines, not in the stomach

We all remember that the digestion process starts as soon as we have sent the first piece of food into our mouth. Saliva contains enzymes that start digestion, soften food and help it pass further down the esophagus. The stomach also begins to release gastric juice for splitting food.

But the main splitting of food does not occur in the stomach, but a little later-when it enters the intestines. At the same time, the same nutrients are formed that the body should have time to assimilate in the fullest possible volume. If there is any heaviness or discomfort after eating, enzyme preparations can be used here. But not all of them are able to reach the intestines at the same time with food or are activated too slowly. Then the body loses a tangible share of “fuel”, and therefore the heaviness and discomfort after eating can last for some time.


In this regard, an enzyme preparation Creon® 10000 can become a faithful assistant. It enters the intestines simultaneously with food and is activated after 15 minutes, eliminating heaviness after eating, abdominal discomfort, bloating, increased gas formation and other unpleasant sensations.3 But most importantly, the nutrients are absorbed correctly and in the right amount. 


 

Fact # 4. Minimicrospheres are the most modern format for enzymes4

Most enzyme preparations contain one and the same active substance — pancreatin. The composition of its enzymes completely coincides with those produced by the pancreas. The subtlety lies in the fact that not every drug is able to deliver the active substance exactly as intended — to the intestines.

The most common forms of release for enzymes are tablets and dragees. But they have a significant drawback. Due to the whole form, the tablets cannot mix evenly with the food in the stomach and pass into the intestines with each portion of it. That is why only a part of them goes into the intestines along with food, which may not be enough for full digestion of everything eaten. At the same time, some of the enzymes can settle in the stomach, and we have already found out that enzyme preparations become useless in the stomach. In addition, tablets can be difficult to swallow, especially for young children and the elderly. Trying to crush or grind them will be a mistake, because this will destroy the protective shell of the tablet, and the acidic environment of the stomach will destroy the enzymes.


Quite another thing is the “smart” capsules for digestion Creon®. Each such capsule contains hundreds of particles-minimicrospheres, with a diameter of approximately 1.15mm3. Such minimicrospheres are patented and are contained only in the preparation Creon®5. It is shown that the smaller the enzyme particles, the more effective the drug3 can work.


In this form, it mixes better with food in the stomach and simultaneously passes into the intestines. What is especially important, in addition to the capsule, each minimicrosphere is protected by an acid-resistant shell. It allows them to “survive” in the acidic environment of the stomach and deliver a maximum of active enzymes directly to the intestines3. Thanks to this mechanism of action, taking Creon® helps digestion become as natural as possible, which ensures complete digestion of food and assimilation of all nutrients.3

Fact # 5. The lack of enzymes affects the entire body

The lack of enzymes affects the entire body6. Overeating also harms other body systems. Filling up with food beyond measure, the stomach obediently stretches the walls and increases in size. So it can put pressure on the organs of the chest, spleen, intestines and interfere with their full-fledged work.

In the long term, constant overeating can lead to obesity6. Extra pounds give an additional load on the heart6. After all, he, as a powerful pump, has to pump blood along a longer route.

Overeating and being overweight can often lead to metabolic disorders7. The joints and spine experience a tremendous load. Extremely dangerous changes occur in the liver. In fact, the liver tissue gradually turns into fat7. Diabetes mellitus and insomnia can often develop8.

To help the body digest food, it needs enzyme preparations. They help to establish the processes of digestion and metabolism, which contributes to the well-coordinated work of other organs and systems.


For symptoms of overeating, 1-2 capsules of Creon® 10000 are enough — this is the optimal amount of enzymes to improve digestion. You can take Creon® for everyone and at any age, even pregnant women and young children from birth9. It is best to do this during a meal or immediately after, with a small amount of water9.


For one reason or another, the body often lacks its own digestive enzymes. The fastest way to make up for their lack is to help enzyme preparations. At the same time, it is important that they work quickly, efficiently and as efficiently as possible. This is the key to full-fledged digestion and productive assimilation of useful substances. And along with them — good health and health of the whole body as a whole.

1. Poltyrev S. S. Physiology of digestion: textbook. manual. – Moscow: Higher school, 2003. – p. 386.

2. Belmer S. V., Gasilina T. V. Digestive insufficiency of the pancreas in children. Differentiated approach / / Breast cancer, Mother and Child. Pediatrics, 2007. – No. 1. 

3. Löhr J. M., Hummel F. M., Pirilis K. T. et al. Properties of different pancreatin preparations used in pancreatic exocrine insufficiency // Eur J Gastroenterol Hepatol., 2009; 21 (9): 1024–31.

4. Gubergrits N. B., Expanding the therapeutic capabilities of enzyme preparations: progress from tablets to minimicrosferon, “RMZH” No. 24 of 19.12.2004, p. 1395.

5. The only pancreatin drug in the form of minimicrospheres registered on the territory of the Russian Federation, according to the State Register of Legal Entities as of 05.04.2019 / Source http://www.freepatent.ru/images/patents/52/2408257/patent-2408257.pdf RU 2 408 364 C2 entry from 17.04.2019 and http://www.freepatent.ru/images/patents/18/2440101/patent-2440101.pdf RU 2 440 101 C2 entry from 17.04.2019.

6. Lyubimova Z. V. Digestive disorders. Effective methods of treatment. – Moscow: Eksmo, 2009. – p. 117.

7. Trofimov S. Ya. The digestive system. Intestinal diseases. – M.: Prosveshchenie, 2005. – p. 201.

8. Yakovlev M. V. Normal human anatomy: lecture notes. – Moscow: Higher School, 2003. – p. 312.

9. Instructions for the medical use of the drug Creon® 10000 from 11.05.2018.

The material was developed with the support of the Abbott Company in order to increase patient awareness about the state of health.

RUCRE191033 from 17.04.2019

Leave a Reply