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Lokren is a beta-blocker preparation responsible for lowering blood pressure and reducing the intensity of the heart rate and its contractions. Lokren is a prescription medicine.
Lokren – action
Action of the drug Lokren is based on the active substance of the preparation – betaxolol. Betaxolol is a substance belonging to the group of beta-blockers (beta-blockers), and its action blocks beta-adrenergic receptors. Beta-adrenergic receptors are found in muscle, nerve and gland cells in many tissues and organs of the human body. Adrenergic receptors are stimulated by adrenaline and noradrenaline, and blocking these receptors reduces the effects of adrenaline on our body. This process lowers blood pressure and reduces the heart rate and the strength of its contractions.
Lokren – application
Lek Lokren It is prescribed in the treatment of arterial hypertension and ischemic heart disease.
Sometimes, however, the patient cannot use the preparation Lokren. This happens in the case of allergy to any of the ingredients of the drug and the diagnosis of such conditions as: bronchial asthma, obstructive pulmonary disease, heart failure, cardiogenic shock, bradycardia, severe form of Raynaud’s syndrome, circulatory disorders in peripheral arteries, phaeochromocytoma, hypotension, second and third degree atrioventricular block, metabolic acidosis, medical history of anaphylactic reaction. Bow Lokren it cannot be used by patients taking floctafenine or sultopride, as well as by pregnant women. Not recommended is taking the drug Lokren during breastfeeding.
Lokren – doses
Lek Lokren it comes as film-coated tablets and is administered orally. Dawki the drug depends on the individual predisposition of the patient, but usually adults take 20 mg of the preparation a day. In patients suffering from impaired kidney function, doses prepared Lokren blood creatinine levels depend – if creatinine clearance is higher than 20 ml / min, the adjustment doses place Lokren It is not necessary. In severe renal failure (creatinine clearance less than 20 ml / min), Lokren dose should not exceed 10 mg per day.
Lokren – side effects
Preparation Lokrenlike any drug, it can cause side effects. Often, patients using Lokren they experience recurring headaches, drowsiness, weakness of the body, there are also vomiting, diarrhea, abdominal pain, decreased libido. Less often when using the preparation Lokren occur side effects such as: psoriatic changes on the skin, depression, lowering blood pressure, heart failure, bronchospasm, aggravation of the existing atrioventricular block or Raynaud’s syndrome. The least common side effects use of the drug Lokren These are paresthesia, vision problems, hallucinations, hyperglycaemia and hypoglycaemia.