Contents
Zahron supports the treatment of hypercholesterolaemia when diet alone is inadequate. How much is zahron and how should it be taken? What is the composition of the drug zahron? What are the contraindications to the use of Zahron? What side effects can it cause? What should worry us when taking Zahron and when to see a doctor?
Zahron – composition
Zahron is a medicine to help treat hypercholesterolaemia when diet and adequate weight loss exercise are inadequate. In addition, zahron can prevent cardiovascular disorders if there are other factors that increase the risk of a heart attack, stroke, or related health problems.
Zahron contains 5 mg of rosuvastatin, which is present here in the form of rosuvastatin calcium. In addition, the drug includes auxiliary substances such as lactose and quinoline yellow.
See also: Symptoms of familial hypercholesterolaemia that everyone should know [EXPLAINED]
Zahron – price
The cost of the drug zahron in the form of 28 film-coated tablets with 10 mg rosuvastatin content costs about PLN 9. The price of the drug zahron 20 mg, packaging with 56 tablets, is about PLN 60.
Zahron – dosage
The dosage of the drug Zahron should be determined individually with the doctor, taking into account the purpose of treatment and the patient’s response. The drug can be taken regardless of the time of day and food consumption.
When treating hypercholesterolaemia, it is recommended to take 5 mg or 10 mg of the drug once a day orally. At the beginning of treatment, the dose is adjusted according to cholesterol levels and the risk of developing cardiovascular disease. The doctor should also take into account the risk of side effects. If necessary, the dose can be increased, but only after medical recommendations. You should not do it on your own, as this is associated with an increased risk of side effects.
If zahron is administered to reduce cardiovascular events, the most common dose is 20 mg once a day.
Zahron is not recommended for children under 10 years of age.
If you miss a dose, just take the next dose as normal as usual. Also, remember not to take a double dose to make up for a forgotten dose.
Your doctor will decide how long you should take Zarzir. This may cause the disease to come back if the patient stops treatment on his own.
If you have any further questions about the use of Zahran, ask your doctor or pharmacist.
See also: Can I take expired medications? The expert explains
Zahron – contraindications
Zahron should not be used in people with hypersensitivity to rosuvastatin, as well as any active substance that is an ingredient of the drug. In addition, it is not recommended to take the drug in patients with liver disease, severe kidney problems, as well as in pregnant, breast-feeding and fertile women (if you become pregnant while taking Zarzad, stop the treatment immediately and inform your doctor). If a woman of childbearing age is taking Zahron, she should use effective contraception at the same time.
Moreover, in the case of administering the drug zahron in a dose of 40 mg, it is a contraindication in people suffering from hypothyroidism, with moderate renal impairment and in patients abusing alcohol.
It is also not recommended for patients with repeated or unexplained muscle aches, taking ciclosporin (a medicine to prevent rejection of an organ transplant), problems with very low blood pressure and narrowing of the aortic heart valve, cardiogenic shock (a condition where the heart does not is able to supply the body with enough blood) or heart failure after a heart attack.
See also: Heart failure is an epidemic of the XNUMXst century
Zahron – side effects
The drug zahron, like any other therapeutic agent, may cause side effects. Most often, the main component of zahron – rosuvastatin – causes mild side effects. These include headache, dizziness, constipation, nausea, abdominal pain, muscle aches, and weakness. However, Zahron can also lead to diabetes, itching, redness and hives, and an increase in the amount of protein in the urine (it usually returns to normal on its own without stopping the drug).
In severe cases, a severe allergic reaction may also occur, symptoms of which include swelling of the face, lips, tongue and / or throat, difficulty swallowing and breathing, severe itching of the skin (with raised lumps). In such a case, you should immediately stop taking Zahron and seek medical attention.
Zahron can also cause very serious (and very rare) side effects including: sudden wheezing, chest pain, shortness of breath or difficulty breathing; swelling of the eyelids, face or lips; swelling of the tongue or throat which causes great difficulty in breathing and / or swallowing; severe skin reactions including severe rash, hives, reddening of the skin all over the body, severe itching, blistering, peeling and swelling of the skin, inflammation of the mucosa (Stevens-Johnson syndrome) or other allergic reactions; myocardial infarction, abnormal heartbeat; inflammation of the pancreas which can cause severe abdominal and back pain accompanied by a feeling of being very unwell. In such cases, please consult your doctor immediately.
Research has shown that chron can have effects on skeletal muscle, resulting in muscle pain. Especially when the drug is administered in doses exceeding 20 mg per day. Gut and stomach disorders, hepatitis, jaundice, nervous system disorders, kidney and urinary tract disorders, as well as respiratory disorders, edema, sleep problems (insomnia and nightmares), depression and lung diseases ( prolonged cough and / or shortness of breath or fever), severe abdominal pain (pancreatitis), increase in liver enzymes in the blood, decrease in the number of platelets in the blood, which increases the risk of bleeding or bruising (thrombocytopenia), trace amounts of blood in the urine, nerve damage legs and hands (e.g. numbness), joint pain, memory loss, gynecomastia (enlarged breasts in men), diarrhea (loose stools), Stevens-Johnson syndrome (severe disease with blisters on the skin, mouth, eyes genitals), damage to the tendons and nerve problems which can lead to weakness, tingling and numbness.
Before taking Zahron, tell your doctor about all the medications you are taking. While taking Zahron, be aware of any side effects and inform your doctor about them.
Zahron – precautionary measures
Before starting treatment with Zahron, inform your doctor about possible kidney disorders, liver disorders, thyroid disorders, severe respiratory failure; recent heart attack, heart failure, increase in blood pressure (hypertensive crisis); unexplained muscle pains (especially if they have already occurred in other family members or when they start taking other cholesterol-lowering medicines).
The patient should also inform the physician if he / she is drinking large amounts of alcohol, as well as about his age.
Before you start taking Zarzon, you should also inform your doctor about the following (possibly):
- other medicines for lowering cholesterol called vibrats (read this leaflet carefully, even if you have used other medicines for lowering cholesterol in the past);
- medicines to treat HIV infection (e.g. ritonavir with lopinavir and / or atazanavir);
- medicines containing fusidic acid (used to treat bacterial infections) by mouth or by injection if you have taken them in the last 7 days; taking Zahron with fusidic acid may lead to severe muscle problems (rhabdomyolysis);
You should know that statins can affect the liver in some people. It is found by performing a simple test that will show increased levels of liver enzymes in the blood. For this reason, your doctor will usually carry out a blood test (liver function test) before and during treatment with Zahron.
People suffering from diabetes or at risk of developing diabetes must remain under strict medical supervision while using the drug. People who are high in sugar and fat in the blood, are overweight and have high blood pressure may be at risk of developing diabetes.
Do not drink grapefruit juice or eat grapefruit while you are taking Zarzir, as these fruits and grapefruit juice may increase the blood levels of the active substance amlodipine, which may in turn exacerbate the blood pressure lowering effect of zahron.
Zahron may cause impairment of the ability to drive vehicles and operate machinery. May cause dizziness when used. If the drug causes nausea, dizziness, tiredness, or headache, do not drive or use machines and contact your doctor immediately.
Keep this medicine out of the sight and reach of children. You should also pay attention to the expiry date of the product and do not use the preparation after its expiry date. The drug should also be stored below 30 ° C in the original package in order to protect from light. Like any other pharmaceuticals, zavir should not be disposed of via wastewater or household waste. Ask your pharmacist how to throw away medicines no longer required.
See also: How long is the prescription valid? Some stop working after a few days
Zahron – interactions with other agents
Like any medication, Bezron may affect any other medication you take, or those other measures may affect your Bezron medication. Therefore, always tell your doctor about all medications you are taking or are taking recently.
Zahron drug interactions include:
- warfarin or clorel (or any other drug used to thin the blood);
- fibrates (e.g. gemfibrozil, fenofibrate) or any other medicine used to lower cholesterol (e.g. ezetimibe);
- indigestion remedies (used to neutralize the acid in your stomach);
- contraceptives;
- Hormone Replacement Therapy;
- ritonavir with lopinavir and / or atazanavir, indinavir, nelfinavir (medicines to treat HIV);
- ketoconazole, itraconazole (anti-fungal medicines);
- rifampicin, erythromycin, clarithromycin (antibiotics);
- medicines containing St. John’s wort (Hypericum perforatum);
- verapamil, diltiazem (heart medicines); dantrolene (used as an infusion for severe abnormal body temperature);
- temsirolimus or other medicines to treat cancer (chemotherapy);
- everolimus, tacrolimus, cyclosporine, or other medicines (used to control the patient’s immune system, allowing the body to accept the transplanted organ);
- simvastatin (a medicine used to lower cholesterol);
- regorafenib (used to treat cancer);
- any of the current drugs in force, including HIV or hepatitis C infection, administered alone or in combination with other drugs: ritonavir, lopinavir, atazanavir, simeprevir, ombitasvir, paritaprevir, dasabuvir, velpatasvir, grazoprevir, elbasvir, glecaprevir, pibrentasvir.
Zarzi must not be taken together with fusidic acid, as this can lead to weakness, tenderness or pain in the muscles (rhabdomyolysis).
Zahron may lower the blood pressure even more in patients who are already taking other antihypertensive drugs.