The best drugs for thrombophlebitis of the lower extremities
When the outflow of blood is disturbed, the walls of the veins become inflamed and blood clots form, the so-called thrombi, thrombophlebitis is diagnosed. The disease has two forms: acute and chronic.

Inflammation can occur in any venous vessels, but thrombophlebitis of the superficial and deep veins of the lower extremities is more common. Thrombophlebitis is dangerous because a blood clot can come off at any moment, and this is already a life-threatening condition. However, timely treatment will help to avoid such complications with thrombophlebitis of the lower extremities.

During conservative treatment, the doctor may prescribe several drugs of various effects: 

  • phlebotonics to strengthen the venous wall; 
  • angioprotectors to improve vascular microcirculation; 
  • anticoagulants, which prevent the formation of blood clots by reducing blood clotting; 
  • anti-inflammatory agents. 

Only complex treatment under the supervision of a doctor will help get rid of thrombophlebitis of the veins of the lower extremities. 

Rating of the top 10 effective remedies according to KP 

Phlebotonics include: 

1. Troxevasin 

One of the most popular drugs for thrombophlebitis of the lower extremities. The active substance – troxerutin – has a property that strengthens the walls of blood vessels and increases the tone of the veins.

The manufacturer notes that the drug is able to reduce inflammation in the vascular wall, limiting the adhesion of platelets to its surface. Indications for use in addition to thrombophlebitis include varicose veins, chronic venous insufficiency and varicose dermatitis.

Troxevasin in the form of a gel is not used if there are violations of the skin (wounds, scratches). 

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2. Detralex

This tool has venoprotective and venotonic properties. Increases venous tone, reduces vein extensibility and venous stasis, thereby helping to overcome thrombophlebitis of the veins of the lower extremities.

The drug is indicated for the treatment of symptoms of chronic venous disease.

Contraindicated during pregnancy, lactation and children under 18 years of age, due to the lack of studies in these groups.

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Angioprotectors include:

3. Phlebodia 600

Diosmin in the composition of the drug improves blood microcirculation and has a decongestant effect. The remedy is indicated for lymphovenous insufficiency of the lower extremities, with sensations of heaviness, fatigue and fullness in the legs, pain and swelling.

Due to limited experience with the drug is not used during pregnancy.

The use of the drug under 18 years is contraindicated.

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4. Angionorm

The drug is used as part of the complex therapy of vascular disorders, helps to improve microcirculation. It is indicated for thrombophlebitis, thrombosis, thromboembolism, varicose veins and post-thrombotic syndrome.

As part of the product – medicinal plant materials: hawthorn, wild rose, horse chestnut.

Not recommended for children under 18 due to lack of clinical safety data. The drug is not used by people with severe chronic liver disease. 

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5. Troxerutin

The drug acts in several directions at once: it helps to improve microcirculation and strengthen the walls of the veins. Used for superficial thrombophlebitis and venous insufficiency, varicose veins and post-thrombotic syndrome.

Not applicable to persons under 18 years of age. At the same time, it is not absorbed into breast milk, therefore it is allowed during breastfeeding. 

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Blood-thinning drugs (anticoagulants) include:

6. Hepatrombin

Contains Heparin, a direct acting anticoagulant. The gel, when applied topically, prevents the formation of blood clots and improves blood flow. Hepatrombin is indicated for thrombophlebitis, thrombosis, varicose veins and sports injuries.

The drug should not be applied to wounds. Also a contraindication is hypersensitivity to the components of the drug.

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7. Eliquis

The active substance is Apixaban. It is prescribed for the prevention and treatment of thrombosis.

Indications of the drug – deep vein thrombosis, pulmonary embolism and other diseases of the veins and blood vessels.

The tool can be used after a course of heparin injections. There are contraindications, so the drug is prescribed exclusively by a doctor. Eliquis can only be purchased at a pharmacy with a prescription.

8. Xarelto 

The drug with rivaroxaban in the composition helps prevent the formation of blood clots. It is used in the treatment of thrombophlebitis, thrombosis and pulmonary embolism and for the prevention of stroke and systemic thromboembolism.1.

Rivaroxaban is contraindicated in patients with liver disease. Use in children has not been studied. The drug is dispensed from pharmacies by prescription.

9. Enoxaparin

Enoxaparin sodium is a drug in the form of a solution for injection. It is used to prevent venous thrombosis.

All patients who take anticoagulants, including pregnant women, are at risk of bleeding.2, therefore, the drug is prescribed by a doctor together with control tests of blood coagulability indicators. Sold in pharmacies by prescription. 

10. Warfarin

Blood-thinning drug for the treatment and prevention of thrombosis and embolism of blood vessels.

The drug has an extensive list of contraindications. So, its reception is not recommended for liver diseases and pregnancy, as well as for people with severe liver or kidney disease.

When using Warfarin, special supervision is necessary for elderly patients. The drug is sold in pharmacies only by prescription. 

Anti-inflammatory agent in the fight against thrombophlebitis is Venolife, it is used for acute and chronic thrombophlebitis.

How to choose drugs for thrombophlebitis

Before starting the use of any drug for the treatment of thrombophlebitis, a specialist consultation is necessary. The doctor will prescribe an examination, diagnose thrombophlebitis of deep or superficial veins, and only then select the necessary dosages of drugs in order to prevent complications and surgery. 

Popular questions and answers

Why is thrombophlebitis of the lower extremities dangerous?
The main danger of varicose veins, thrombophlebitis and other vein problems is pulmonary embolism. This is a life-threatening condition caused by a dislodged blood clot. Medical care not provided in time can lead to cardiac arrest.
Does the diet help with thrombophlebitis of the lower extremities?
Doctors recommend that patients with thrombophlebitis follow a certain diet: eat beef liver to strengthen the walls of blood vessels, add vegetables, cereals and herbs to the diet. Meat is better to prefer seafood. It is impossible to cure thrombophlebitis with a diet, but you can help your body by following the doctor’s instructions about proper nutrition.
Is it possible to treat thrombophlebitis of the lower extremities with folk remedies?
Self-medication with the use of drugs with unproven effectiveness can aggravate the course of thrombophlebitis. A timely visit to the doctor will help to start adequate treatment and prevent the development of irreversible consequences.
When are antibiotics used for thrombophlebitis of the lower extremities?
After the infection that caused thrombosis is diagnosed, the doctor may prescribe antibiotics for treatment, but it is better to entrust the selection of all drugs to combat thrombophlebitis to a specialist.
  1. Guidelines for the practical use of the drug Xarelto dated 28.08.2019.
  2. Instructions for use Enoxaparin sodium solution for injections.

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