Alendronic acid

General aging of the body and menopause and often cause the destruction of the body’s bone tissue. The consequences of this process are very dire. That is why you have to devote so much time and effort to stopping the development of such diseases.

There can be several reasons for the appearance of osteoprosis and a number of other bone tissue diseases. These include smoking, genetic predisposition, metabolic disorders, and a sedentary lifestyle.

For more effective treatment of osteoporosis in healthcare settings, alendronic acid often comes to the rescue. This substance inhibits the aging of bone tissue, its thinning, moreover, alendronic acid is not based on hormones, which makes it indispensable in the fight against osteoporosis and a number of other diseases.

 

Unfortunately, there are no products in nature that contain alendronic acid. Alendronic acid is a synthetic element obtained by artificial means.

However, within the framework of osteoporosis therapy for bone destruction, nutritionists often prescribe an appropriate nutritional program that allows you to combine the intake of alendronic acid with a diet that contributes to more effective treatment of osteoporosis.

Foods with the highest levels of nutrients needed to fight bone breakdown:

Caution should be exercised with products such as coffee, coca-cola and other caffeinated formulations that interfere with calcium absorption. Mayonnaise, margarine and spreads, lard and lamb fat also interfere with the absorption of calcium, impairing its absorption in the intestines. Alcohol, as well as smoking, acts in the same way on the body.

General characteristics of alendronic acid

Alendronic acid is a synthetic prototype of the substance pyrophosphate. The acid belongs to the class of bisphosphotanes, the full name is aminobiphosphonate… It is a white powder that dissolves well in water.

Once in the body, alendronic acid quickly penetrates into soft tissues, after which it reaches the bones. It is excreted along with urine. In the human body, alendronic acid does not go through the metabolic stage. Alendronate is embedded in bone tissue, preventing its premature destruction.

The daily human need for alendronic acid:

For the prevention of osteoporosis, doctors recommend taking 5 mg of this substance per day. With the development of osteoporosis, it is recommended to take alendronic acid in an amount of 10 mg per day. If a person suffers from Paget’s disease, it is recommended that he take 40 mg per day for six months.

Rules for taking alendronic acid

Alendronic acid is recommended to be taken in the morning on an empty stomach with a glass of water. It is not recommended to use before going to bed. For the same reason, it is not recommended to take a horizontal position immediately after taking the substance for 30 minutes. This simple rule will help you avoid the development of esophagitis (inflammation of the lining of the esophagus).

The need for alendronic acid increases:

  • in osteoporosis;
  • with more frequent bone fractures;
  • with hypercalcemia;
  • at menopause;
  • with Paget’s disease.

The need for alendronic acid is reduced:

  • with increased sensitivity to the substance;
  • during pregnancy;
  • during lactation;
  • in childhood;
  • with gastritis;
  • with stomach and duodenal ulcers;
  • with achalasia of the esophagus;
  • renal failure;
  • in dysphagia;
  • with a deficiency of vitamin D;
  • with hypocalcemia.

Absorption of alendronic acid

For a more complete assimilation of alendronic acid, the drug is recommended to be drunk two hours before meals. The substance has been proven to be less absorbed when taken on a full stomach. And if at the same time you drink coffee or tea, soda, or orange juice, then the percentage will decrease even more. But ranitidine will double the absorption.

Useful properties and effects on the body

Osteoporosis is characterized by a decrease in bone mass. This increases the risk of fractures of the hip, spine, and wrist.

Alendronic acid is used to prevent and treat this disease, as well as some other problems (Paget’s disease and calcium metabolism disorders).

Alendronic acid increases bone mineral density and promotes the formation of normal bone tissue.

Interaction with other elements:

Alendronic acid actively and differently interacts with the elements. For example, vitamin C enhances the possible side effects of taking a substance, and magnesium hydroxide reduces its absorption. Calcium carbonate and calcium chloride act similarly. But ranitidine, on the contrary, doubles the percentage of assimilation of alendronic acid whole!

Lack and excess of alendronic acid:

Signs of alendronic acid deficiency

Since alendronic acid is an artificially created compound, there can be no signs of its lack in the body.

Signs of excess alendronic acid

With frequent or excessive intake of alendronic acid, people experience the following symptoms:

  • stomach ache;
  • constipation or diarrhea;
  • flatulence;
  • an ulcer of the esophagus;
  • pain in the bones;
  • pain in the muscles;
  • joint pain;
  • headache;
  • dyspepsia.

Factors affecting the content of alendronic acid in the body

As already mentioned, alendronic acid is a synthetic element, which means that the first factor is the conscious and correct intake of the drug in accordance with the doctor’s instructions.

Secondly, it significantly affects the absorption of acid in the body and the way alendronic acid is used. Acid is better absorbed before meals – on a full stomach, alendronic acid simply won’t be absorbed at all.

Thirdly, studies have shown that with prolonged use, addiction occurs and the body stops responding to alendronic acid.

Fourthly, the use of alendronic acid, together with substances incompatible with it, significantly reduces its absorption.

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