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Nitrendipine is a dihydropyridine derivative, second generation calcium antagonist. It inhibits the penetration of calcium ions into smooth muscle cells in peripheral arteries. Thus, it contributes to the improvement of cerebral and pulmonary circulation and to lowering blood pressure. It does not reduce blood flow through the kidneys. It is well absorbed from the gastrointestinal tract and works for a period of 8-12 hours. It does not accumulate in the body – it is excreted in metabolic processes.
Indications for the use of Nitrendipine
Nitrotypical is used to treat essential hypertension. It can be the drug of first choice and the only one used in the treatment of this ailment, and it can be combined with other medications to lower blood pressure.
Dose Nitremypinya is selected individually for a given patient. Usually it is 5 to 10 mg Nitremypinya once a day. This dose can be gradually increased.
When should you not use Nitrendipine?
Contraindications to receive Nitremypinya is hypersensitivity to nitrotype, other calcium antagonists or any component of the formulation. Nitremypinya It can also not be used in the case of cardiogenic shock, hypotension, main artery stenosis, after a recent myocardial infarction, in unstable angina, as well as during pregnancy and breastfeeding.
The use is not recommended Nitremypinya in children and adolescents under 18 years of age.
Possible side effects of using Nitrendipine
Nitrendypina enhances the effect of other antihypertensive drugs. In the initial phase of treatment, there may be an excessive loss of sodium in the urine. The drug may increase the effect of muscle relaxants.
Headaches, flushing and peripheral edema may occur. Rarely, tachycardia (increased heart rate), diarrhea, vomiting, abdominal pain, frequent urination, pain in muscles and joints, hypotension, weight gain, allergic reactions occur. Very rarely when used Nitremypinya myocardial infarction, leukopenia, gingival hyperplasia, angioedema, fever, gynecomastia (enlargement of the mammary glands in men), menstrual bleeding may occur.
See also: The male problem of female breasts
Precautions when taking Nitrendipine
Use with caution Nitremypinya in patients with renal or hepatic insufficiency, as the effect of the drug may then be increased or prolonged. Caution should also be exercised in the case of sick sinus syndrome.
During treatment with the preparation Nitrendypina special attention should be paid to proper oral hygiene, as taking medications with calcium antagonists may cause gingival enlargement.
Nitrendypina interacts with some cardiac drugs and increases the concentration of digitalis glycosides in the blood. It also comes in unwanted reactions with grapefruit juice.
In the initial stage of application Nitremypinya, because of the possible side effects fainting and heart problems, special care should be taken when driving or operating machinery.