Many hesitate before resorting to aesthetic injections, in particular for the face, but the new injection techniques and especially the revolution represented by the antidote of hyaluronic acid (the most widely used filler), namely hyaluronidase, reduces with reason the hesitations.

The face may become sad, tired, or severe. You may want to show more cheerfulness, rest or friendliness. It is then that we use the so-called aesthetic injections. Indeed, the injection of a more or dense gel depending on the targeted areas allows:

• to fill a crease or a wrinkle;
• to erase fine lines around the mouth or at the corners of the eyes;
• to re-hem the lips (which have become too thin);
• restore the volumes;
• to correct hollow dark circles.

The bitterness folds (which descend from the two corners of the mouth) and the nasolabial folds (between the wings of the nose like nasolabial and the corners of the lips towards the chin like genius) are the most frequent marks of this severity of the face.

Before tackling hyaluronidase, we must take a look at hyaluronic acid. It is a molecule naturally present in the subcutaneous tissue. It participates in its deep hydration by maintaining water in the skin. It is contained in many skin care creams for its moisturizing and smoothing effects.

It is also a synthetic product used for these famous aesthetic injections for:

• fill in wrinkles;
• restore volumes;
• and deeply hydrate the skin.

It is the safest filler on the market; it is degradable and non-allergenic.

The first injections had “failures”: they left bruises (bruises) but the use of micro cannulas considerably reduced their risk of occurrence. The effects are visible in 6 to 12 months but it is necessary to renew the injections every year.

Very rarely, but it does happen, so-called aesthetic injections cause bruising (bruising), redness, edema or small balls under the skin (granulomas). If these side effects persist beyond 8 days, the practitioner should be notified.

These “incidents” occur:

• either because hyaluronic acid is injected in too large a quantity;
• or because it is injected too superficially when it must be in depth.
  

For example, by wanting to fill hollow dark circles, we create bags under the eyes that could persist for years without the hyaluronic acid being absorbed.

Another example: the formation of small balls (granulomas) on the bitterness folds or the nasolabial folds that we have tried to fill.

Hyaluronic acid is absorbable after one or two years and it is perfectly tolerated by the body. But in addition, there is an antidote that instantly reabsorbs it: hyaluronidase. For the first time, a filler has its antidote.

Hyaluronidase is a product (more precisely an enzyme) that breaks down hyaluronic acid.

We had already noticed, at the beginning of the XNUMXth century, that the extracellular matrix is ​​essentially composed of hyaluronic acid which lowers tissue viscosity and thus increases tissue permeability.

Thus, in 1928, the use of this enzyme began to facilitate the penetration of vaccines and various other drugs.

It is part of the composition of products injected in mesotherapy against cellulite.

Hyaluronidase instantly dissolves the hyaluronic acid injected as a supplement or filler during cosmetic injections, which allows the operator to “take back” the targeted area and thus correct the small damage observed:

• dark circles;
• blisters;
• blue;
• granulomes ;
• visible hyaluronic acid balls.

Aesthetic medicine and cosmetic surgery are no longer taboo. They are used more and more.

According to a Harris poll in 2010, 87% of women dream of changing some part of their body or their face; they would if they could.

The survey does not detail this: “if they could” financial question, question of self-authorization or authorization of others, or others…?). It should be noted in passing that the prices of hyaluronic acid or hyaluronidase injections vary greatly between the products used and the areas concerned: from 200 to 500 €.

Another survey (Opinionway in 2014) shows that 17% of women and 6% of men consider using injections to reduce facial wrinkles.

Aesthetic injections, especially accompanied by the promise of a miracle antidote, have a bright future ahead of them.