Zotral – application, action, description

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Zotral is a medication for depression and is only prescribed by a doctor. Its task is to treat depression and prevent its recurrence. In addition, the preparation treats panic disorder and obsessive-compulsive disorders. What is its dosage? How does Zotral work? What are the side nipples?

Zotral – when is it used?


Zotral is intended for the treatment of major depressive disorders. And obsessive-compulsive disorder, and in preventing recurrence of major depressive episodes. In drug seizure states with and without aerophobia. Zotral is also indicated for combating post-traumatic stress disorder, social anxiety disorder. This drug is used in adults and pediatric patients 6-17 years of age.

Zotral – how does it work?


Zotral contains, as a strong antidepressant, sertraline, which belongs to the group of serotonin reuptake inhibitors. Serotonin is one of the neurotransmitters, substances that play an important role in communication between neurons at a site known as the synapse. It has a very weak effect on the reuptake of norepinephrine and dopamine. Following an oral dose of 50-200 mg once a day for 14 days, peak plasma levels were reached 4,5-8,4 hours after the daily administration of the drug. Plasma protein binding is about 98%. Sertraline is extensively metabolised during its first pass through the liver

Zotral – dosage

Zotral is an oral medication prescribed only by a doctor for the treatment of a specific disease, the dosage should be strictly adhered to the doctor’s instructions. The drug should be taken in the morning or evening, regardless of the meal, washed down with a sufficient amount of water.

Adults:

For the treatment of depression and obsessive-compulsive disorders

the usual dose is 50 mg per day, but a maximum of 200 mg per day if the doctor decides to increase the dose.

To maintain treatment and prevent relapse, the drug can be used in minimal doses for at least 6 months. Your doctor will periodically assess your response to treatment and adjust the dose as necessary.

When treated with panic disorder, post-traumatic stress disorder and social anxiety disorder:

at the beginning, the dose is 25 mg daily. After one week, the dose should be increased to 50 mg daily. Your doctor may decide to gradually increase the dose to a maximum of 200 mg per day, if necessary.

Children and adolescents from 6 to 12 years of age:

For obsessive-compulsive disorder:

At the beginning of the treatment, the dose is 25 mg a day, this may be increased to a maximum of 200 mg a day if your doctor tells you so.

Children and adolescents from 13 to 18 years of age:

Obsessive Compulsive Disorder:

For obsessive-compulsive disorder:

At the beginning of the treatment, the dose is 25 mg a day, this may be increased to a maximum of 200 mg a day if your doctor tells you so.

The clinical effects of the drug may appear after 7 days of treatment. As with other antidepressants, optimal treatment effects only take longer to develop.

Zotral – side effects


Like all drugs, Zotral can cause side effects in both adults and children. The most common side effects when taking Zotral are: insomnia, somnolence, anorexia; tremor, dizziness, dry mouth; nausea, diarrhea, sexual dysfunction (mainly in men), fatigue, hot flushes, yawning, agitation, restlessness, headache, movement disorders, tremors, increased sweating; indigestion, constipation, abdominal pain, vomiting, chest pain, palpitations, skin rash, visual disturbance, tinnitus, menstrual disorders. Hypersensitivity reactions, allergy, nightmares, aggressive behavior, psychosis, involuntary muscle contractions, coma, convulsions. Isolated cases of withdrawal symptoms such as agitation, restlessness, headache and dizziness, nausea and tremor have been reported after discontinuation of sertraline treatment.

Before use, read the leaflet, which contains indications, contraindications, data on side effects and dosage as well as information on the use of the medicinal product, or consult your doctor or pharmacist, as each drug used improperly is a threat to your life or health.

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