What gives you super resistance to COVID-19? Two ways. Scientists studied which one was more effective

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Can you be super immune to COVID-19? After two years of the pandemic, people are still asking themselves this question. Scientists know it is possible, and they know when it is. Moreover, a study just published in Science Immunology revealed that the body builds up such super-immunity in response to two situations. Get to know the details.

1. Natural coronavirus infection followed by COVID-19 vaccination and breakthrough infection after vaccination build super-immunity to coronavirus
2. Scientists from Oregon Health & Science University (OHSU) in the US have studied which of these combinations is more effective
3. The study showed that there is no significant difference here. – Either way, you’ll get a really strong immune response – amazingly high – said the co-author of the work of Dr. Fikadu Tafesse
4. Researchers point out that a natural infection itself provides short-term protection, pointing to the importance of vaccination against COVID-19
5. The scientists’ findings cannot be taken as an incentive to expose oneself to the coronavirus infection
6. More information can be found on the TvoiLokony home page

Super-resistance to COVID-19. Scientists are investigating two combinations

During the two years of the COVID-19 pandemic, almost 360 million cases were reported worldwide. 2 million people have lost their lives due to or with SARS-CoV-5,6 and the number of people is still increasing (as are infections). We don’t know what else awaits us. So it’s no surprise that super-immune people and generally extremely strong protection against the coronavirus are attracting a lot of attention – not just scientists.

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Among us, there are people who still managed to escape the pathogen, despite regular exposure to it. Researchers suspect that this type of super-resistance may be due to genes or previous regular exposure to different types of microbes (e.g. in a hospital). More on this in the article: A medical phenomenon. They are super immune to the coronavirus.

The rest of the text is below the video.

The body can achieve exceptional resistance to SARS-CoV-2 in another way – there are actually two possibilities. And they were the focus of scientists from Oregon Health & Science University (OHSU) in the USA. They described the results in a work just published in the journal “Science Immunology”. Natural coronavirus infection and subsequent COVID-19 vaccination and vaccination breakthrough infection have been known to build super-immunity to the coronavirus. Which of these combinations gives the best effect? This was the purpose of the work of the scientists at OHSU. Before them, no one had studied this issue.

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Infection before and after vaccination – what is immunity built up?

104 volunteers participated in the study. Of this group, 31 were fully vaccinated and had a breakthrough infection confirmed by PCR. Another 31 people underwent COVID-19 prior to vaccination. The remaining 42 people were fully vaccinated and had not had SARS-CoV-2 infection to date. Serum samples were collected from all of them and tested for antibody concentrations. As it turned out?

«Compared to vaccination alone, SARS-CoV-2 infection before or after vaccination gives a much greater boost to a neutralizing antibody response. More importantly, the strength and extent of antibody responses appear to be improving at the same time, »the researchers write in the above-mentioned paper. Moreover, «it has been proven that the natural infection itself provides short-term protection, indicating the importance of vaccination, regardless of the history of the infection. Since vaccination protects against serious illness and death, it is safer to vaccinate before than after a natural infection ».

As for whether a natural infection had a better effect or a breakthrough in combination with vaccination, the study found that there was no significant difference. “It doesn’t matter if you get infected and then vaccinated or if you get vaccinated and then have a breakthrough infection” – noted in the statement the co-author of the work, Dr. Fikadu Tafesse, assistant professor of molecular microbiology and immunology at OHSU School of Medicine. “In either case, you’ll get a really strong immune response,” surprisingly high, he stressed.

Super-resistance to COVID-19. Three important notes

There are some important points to note. First thing: study co-author Dr. Marcel Curlin emphasizes that immunity obtained from natural infection is variable: some have a strong immune response, others not. Importantly, however, vaccination with an infection response almost always provides very strong protection.

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The second point is that the above-mentioned findings should not be considered as an incentive to risk becoming ill.

The last thing is that the analyzes were done before Omikron came along. And while scientists expect his immune response to be similar, there is no evidence (yet) for this moment.

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