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What does an increased level of monocytes indicate in a child? Could high monocytes result from frequent infections? Is it a symptom of serious diseases, e.g. hematological? What tests are worth doing? The question is answered by the drug. Anna Mitschke.

What do high monocytes indicate in a child?

Hello, I got my daughter’s blood test results and I’m worried elevated monocytes. The tests were commissioned by a pediatrician because the daughter had a lot of infections that appeared almost one after the other. I have the impression that there is no immunity at all and any contact with the virus causes disease. For this reason, the doctor ordered tests and it turned out that monocytes in a child are above normal which worried me a bit.

Could the doctor explain to me exactly what they are saying elevated monocytes in a child? Whether high monocytes in a child justify such frequent infections? I am afraid that this may be a symptom of some more serious problems, and such high monocytes never showed up in my daughter’s research. I also read that elevated monocytes in a child may be a symptom of some more serious hematological diseases – is that true? Is there a chance that frequent infections and high monocytes in a child are a symptom of a more serious disease? Will it be possible to determine immediately or is it an indication for some more detailed research?

The doctor explains what the elevated monocytes indicate

Blood count is a commonly performed test. It consists in determining the number of morphotic elements of blood and allows the assessment of some of their features. In the blood there are, among others white blood cells, otherwise known as leukocytes. These cells are part of the immune system. Leukocytes are a large group of cells, which include: neutrophils (neutrophils), eosinophils, basophils (basophils), lymphocytes and monocytes. The microscope examines the percentage share of each subpopulation of leukocytes. Normally, the percentage of monocytes in the blood is 4-8% of all leukocytes.

The absolute number of monocytes in the blood it is in the range of 30-800 / µl. The increase in the amount of monocytes in the blood is called monocytosis. Monocytes detect where inflammation is taking place and then go there to fight the microbes. Increasing the level of monocytes does not always mean a dangerous disease. We observe monocyte growth in the course of various infections. Typically, the causes of monocytosis are mild. Infections caused by a number of pathogens mobilize the immune system, which results in an increase in the amount of monocytes in the blood.

Monocytosis can occur in the course of more serious disease states. Increasing the number of monocytes is observed in infective endocarditis, systemic diseases of connective tissue, inflammatory bowel diseases, tuberculosis or cirrhosis of the liver. Unfortunately, monocytosis is also observed in the course of neoplastic diseases, e.g. leukemia. The complete blood count should be assessed as a whole while having all the results. Additionally, the examination analysis is based on the clinical picture. An important issue is the patient’s condition, medical history, and presented symptoms. Therefore, I suggest you go to the pediatrician who will have the opportunity to examine the child. The doctor will decide on the need for further diagnostics and, if necessary, will start appropriate treatment.

— Lek. Anna Mitchke

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