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What is creatinine? What role does it play in the human body? What are the applicable norms of this indicator? What is the relationship between creatinine and contrast MRI? The question is answered by the drug. Anna Mitschke.
Based on what standards is the creatinine result analyzed?
Good day. I would like to ask what they are creatinine norms? My mother will have an MRI performed and the doctor recommended that it be done before giving the contrast creatinine test. I do not know the results yet, but I would like to ask what are the creatinine norms and when my mother may have a problem with the performance magnetic resonance imaging with contrast?
Do contraindications in such a situation appear often and will the increased level of creatinine actually be so dangerous that it will not be possible to perform the test? By the way, I would also like to ask about creatinine standards apart from contrast to magnetic resonance imaging and computed tomography.
In such a situation, do creatinine norms differ significantly? And what can an increased or decreased creatinine level in a blood test show? Could this indicate some disease or other health problems, or is creatinine used only to determine the possibility of using contrast? I would be grateful for clearing up my doubts.
The doctor gives the norms for creatinine
Creatinine is a metabolic product, and more specifically it is formed as a result of the degradation of creatine and phosphocreatine. It is measured in serum, plasma and urine. Its concentration depends on the muscle mass and on the creatine supplied in the diet (in meat, dietary supplements). Creatinine is excreted by the kidneys. Therefore, it is used in diagnostics as an indicator of kidney function. In patients with normal renal function, creatinine levels remain relatively constant.
Its normal concentration is in the range of 0,6-1,3 mg / dl. Values above normal indicate worsening of renal excretory function. The cause could be acute either chronic renal failure. Based solely on creatinine values disease cannot be recognized.
This is not an ideal indicator of impaired kidney function, as its increase is noticed relatively late. Elevated creatinine levels we observe only when about half of the renal parenchyma is inactive. From your creatinine value, you can calculate a more accurate kidney function rating – GFR (glomerular filtration rate).
Creatinine may be at the upper end of normal range in people with high muscle mass. Additionally, falsely elevated results are obtained from samples where the blood has undergone hemolysis. Creatinine values below the normal range may indicate cachexia, low muscle mass, an amputee, a vegetarian diet or pregnancy. Radiological contrast agents used in radiology for better visualization of the image can cause damage to the kidneys.
Therefore, the function of these organs should be assessed before administering them. In order to prevent the occurrence of complications, the following are used, inter alia, irrigation. In the case of incorrect values, the doctor decides whether the patient is qualified for the examination. Sometimes it is necessary to consult a nephrology specialist and to deepen the diagnosis. In addition, before the examination, it is important to take a history taking into account the burden of kidney diseases and to examine the patient.
— Lek. Anna Mitchke
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