Vitaminum A + E Medana – indications, dosage, contraindications, side effects

Vitaminum A + E is a preparation used in family medicine to supplement the diet with vitamins A and E. Vitaminum A + E is administered to patients with a deficiency of these vitamins or the expected greater demand of the body. The drug is available in capsule form and can be obtained without a prescription.

Vitamin A+E Medana (Medana)

Indications for the use of Vitaminum A + E

The active substances of the preparation are retinol and tocopherol. Vitaminum A + E is administered:

1. preventively in the case of vitamin A and E deficiencies,
2. in twilight amblyopia,
3. supportive in ischemic heart disease, arterial hypertension, prevention of atherosclerosis, thrombotic vasculitis, hemolytic anemia, diabetes, treatment of tardive dyskinesia, collagenosis.

Dosage: Youth and adults – 1 capsule 1-2 times a day.

Vitaminum A + E and contraindications and warnings

Contraindications to the use of Vitaminum A + E are:

1. hypersensitivity to any component of the preparation,
2. vitamin K deficiency,
3. malabsorption syndrome with waxy stools,
4. severe liver failure or cirrhosis,
5. biliary obstruction,
6. conditions after anastomosis of the jejunum and the ileum.

Vitaminum A + E – warnings

1. The prothrombin time should be monitored during the use of vitamin E (especially in a dose greater than 300 mg daily) and oral anticoagulants.
2. Use of the preparation in pregnant and breastfeeding women only after consulting a doctor and only in accordance with his recommendations.
3. Caution is advised as excessive vitamin A intake may lead to teratogenic effects.

Vitaminum A + E – interactions with other drugs

1. The absorption of vitamin A and vitamin E from the gastrointestinal tract is reduced in the presence of cholestyramine, colestipol, neomycin, liquid paraffin.
2. If it is necessary to administer vitamins A and E and the above-mentioned drugs in parallel, the longest possible time interval between the preparations should be kept.
3. Both vitamin A and vitamin E enhance the anticoagulant effect of coumarins.
4. Concomitant use of oral anticoagulants should be avoided due to the increased risk of bleeding. If it is necessary to use them, the prothrombin time should be monitored.
5. Vitamin E used in conjunction with iron salts may make them less effective in treating iron deficiency anemia.

Vitaminum A + E – side effects

The preparation is well tolerated. In adults, fatigue, muscle weakness, headache and nausea may occur in the case of high doses. The intake of vitamin E at a dose of 3200 mg daily for 7-9 weeks resulted in cramping abdominal pain, diarrhea and nausea.