Vitamin C 500 Prolongatum Pliva – action, indications, dosage, contraindications

Vitamin C 500 Prolongatum Pliva is a preparation used in vitamin C deficiency, prevention of vitamin C deficiency in cases of increased demand and as a supplementary treatment in colds and flu. The preparation is in the form of tablets for oral administration and is issued without a prescription.

Vitamin C 500 Prolongatum Pliva (Pliva Krakow)

ACTION

Vitamin

Indications for taking Vitamin C 500 Prolongatum Pliva

Vitamin C 500 Prolongatum Pliva is a drug recommended:

1. in deficiencies of vitamin C,
2. prophylactically in vitamin C deficiency in case of intense demand,
3. as adjuvant treatment for colds and flu.

Dosage

Vitamin C 500 Prolongatum Pliva is in the form of tablets to be taken orally.

1. Adults. Orally. 500-1000 mg / d.

Vitamin C 500 Prolongatum Pliva and contraindications

Contraindications to the use of Vitamin C 500 Prolongatum Pliva are:

1. hypersensitivity to any component of the preparation,
2. should be used with caution in patients with increased urinary oxalate content or a history of nephrolithiasis, decreased glucose-6-phosphate dehydrogenase, haemochromatosis, thalassemia or sideroblastic anemia.

Vitamin C 500 Prolongatum Pliva – warnings

1. Vitamin C in Vitamin C 500 Prolongatum Pliva may interfere with some laboratory tests (e.g. urine glucose [sugar], plasma ethyl estradiol, lactate dehydrogenase, liver transaminases, bilirubin, oxalate and uric acid levels in urine, plasma iron and ferritin levels).
2. Ascorbic acid, taken in therapeutic doses, may cause false negative results in faecal occult blood tests.
3. Pregnant and breastfeeding women should consult a doctor before taking Vitamin C 500 Prolongatum Pliva.
4. During pregnancy and breastfeeding, ascorbic acid doses should not exceed the daily requirement (80-100 mg per day).

Vitamin C 500 Prolongatum Pliva and other substances

1. Vitamin C increases the effect of increased iron absorption from the gastrointestinal tract and may increase the toxicity of iron preparations.
2. The preparation Vitamin C 500 Prolongatum Pliva may increase the effect and toxicity of oral anticoagulants and sulphonamides.
3. Vitamin C used in high doses (over 1 g per day) causes acidification of the urine, which reduces the excretion of acidic drugs and increases the excretion of alkaline drugs.

Vitamin C 500 Prolongatum Pliva – side effects

Long-term high doses of Vitamin C 500 Prolongatum Pliva (more than 1 g per day) may cause:

1. diarrhea
2. nausea,
3. vomiting,
4. heartburn
5. stomach cramps
6. sudden reddening of the skin,
7. hot flashes
8. Headache,
9. insomnia,
10. may contribute to the formation of calcium oxalate urolithiasis (causing oxalate crystallization in the urine),
11. the use of vitamin C in patients with glucose-6-phosphate dehydrogenase deficiency may cause haemolytic anemia.