Vegantalgin H with analgesic effect. Drug interactions and side effects

Vegantalgin H is a drug used to treat and prevent ailments related to dysmenorrhea, renal colic, hepatic colic, irritable bowel syndrome. Vegantalgin H is a two-component preparation of paracetamol and hyoscine butylbromide, the first substance relieves pain, while the second has a diastolic effect. The drug may be in the form of tablets and rectal suppositories and is available without a prescription.

Vegantalgin H (GlaxoSmithKline Pharmaceuticals SA – Polska)

Ventalgin H – action

Vegantalgin H is a combined preparation with analgesic and diastolic effects. It is a two-component drug containing paracetamol and hyoscine butylbromide.

Vegantalgin H – indications and dosage

Vegantalgin H is a drug taken to relieve pain:

1. painful menstruation,
2. renal colic
3. hepatic colic,
4. accompanying irritable bowel syndrome (prevents it).

Drug dosage

Do not exceed the dose of 6 tablets a day. The preparation can be taken regardless of meals. Vegantalgin H is in the form of rectal tablets and suppositories.

1. Adults and children over 12 years of age. Orally. 1-2 tablets up to 3 × / d, every 8 h; max. 6 tablets / day
2. Rectally. 1 suppository 3-4 × / d, every 6 h; max. 4 suppositories / d.

Vegantalgin H contraindications

Contraindications to the use of the drug Vegantalgin H are:

1. hypersensitivity to any component of the preparation or atropine,
2. severe liver failure (mainly in patients with alcoholic liver disease) or kidney failure,
3. alcoholism,
4. anemia,
5. congenital lack of glucose-6-phosphate dehydrogenase,
6. myasthenia gravis,
7. glaucoma,
8. prostatic hyperplasia,
9. gastrointestinal strictures, tachycardia.

Vegantalgin H – warnings

1. Do not use the drug for more than 3 days (in children) and no longer than 10 days (in adults) without consulting a doctor.
2. Other paracetamol-containing medicines should not be taken concomitantly due to the risk of overdose.
3. Caution should be exercised in patients with mitral orifice stenosis, coronary artery disease, intestinal ulcers, gastroesophageal reflux and other disorders of the smooth muscle function of the upper gastrointestinal tract.
4. People allergic to acetylsalicylic acid derivatives should exercise caution due to the possibility of allergy.
5. Patients who consume alcohol regularly and are starved run the risk of liver damage while taking the drug.
6. Elderly people should exercise caution.
7. Treatment should be discontinued if central nervous system disturbances, dry mouth, urinary retention and visual acuity or pain in the eyeball occur.
8. You must not drink alcohol while taking the drug.
9. Pregnant women should only take the medicine if the doctor decides that the benefits for the pregnant woman outweigh the possible risks for the baby.
10. The preparation should not be taken during breastfeeding.
11. Do not drive while taking Vegantalgin H (eye accommodation may be disturbed and nervous system symptoms may appear).

Vegantalgin H a inne leki

1. Paracetamol enhances the action of anticoagulants from the group of coumarin and indandiion derivatives and caffeine.
2. When administered orally, metoclopramide accelerates (and scopolamine) delays the absorption of paracetamol from the gastrointestinal tract.
3. The elimination of paracetamol is prolonged with the use of salicylamide.
4. Agitation and high fever may be induced when used concomitantly with MAO inhibitors.
5. The use of rifampicin, antiepileptics and hypnotics simultaneously with the preparation and alcohol may cause liver damage.
6. Non-steroidal anti-inflammatory drugs in combination with paracetamol cause impairment of renal function in patients with renal insufficiency.
7. Tricyclic antidepressants, MAO inhibitors, quinidine, amantidine, disopyramide, butyrophenone may increase the anticholinergic effect of the preparation components, cause agitation and high fever.
8. Hyoscine butylbromide reduces motility and secretion in the gastrointestinal tract, which may reduce the absorption and pharmacological effect of orally administered drugs.
9. The effect of the drug on the gastrointestinal tract may be reduced when taking dopamine antagonists (e.g. metoclopramide).

Vegantalgin H – side effects

1. The following may occur: dry mouth, accommodation disorders, disorientation, memory impairment, dizziness.
2. Very rarely, the following may occur: allergic reactions (pruritus, urticaria, rash, erythema, angioedema), increased heart rate, hypotension, nausea, vomiting, diarrhea, retinal discoloration, glaucoma, impaired liver and kidney function, methaemoglobinaemia, agranulocytosis and thrombocytopenia.