The world’s first breast cancer vaccine enters its clinical stage

This could be a real breakthrough in oncology. The US FDA has just agreed to start the clinical phase of research on the world’s first breast cancer vaccine. It is intended to protect healthy women and patients who have already defeated cancer. The vaccine is supposed to work on one type of cancer – triple negative.

1. In 2020, 20 thousand. Polish women were diagnosed with breast cancer. In our country, we have a growing trend in terms of mortality from this cancer
2. Triple negative breast cancer is especially tricky because it does not respond to available therapies. At the moment, a preventive measure for this type of cancer is mastectomy
3. Clinical trials will involve patients with triple negative breast cancer. The goal is to stop the cancer from coming back
4. More information can be found on the Onet homepage

The breast cancer vaccine is entering clinical trials

Until now, work on the world’s first breast cancer vaccine has been limited to animal testing and laboratory research. The preparation has not yet been administered to humans. Now that is about to change, thanks to the green light from the US Food and Drug Administration (FDA). The clinical phase in women becomes a fact.

1. See also: Atypical symptoms of breast cancer. The oncologist advises what to look for

At the moment, the vaccine for the most aggressive breast cancer will be given to patients who have been diagnosed with triple-negative breast cancer and have managed to overcome the disease. Administration of the preparation may be a chance for them to avoid the recurrence of the cancer. And for women around the world, it is a hope for a breakthrough. If the research is successful, all patients at risk, such as carriers of the BRCA1 gene mutation, will soon be able to receive the world’s first vaccine against breast cancer.

– In the long term, we hope that this may be a real prophylactic vaccine that can be administered to healthy women to prevent them from developing triple negative breast cancer – a cancer for which we have the least effective treatments – wrote Dr. G. Thomas Budd in the press release from Cleveland Clinic’s Taussig Cancer Institute.

The rest of the text is below the video.

How will the cancer vaccine be given?

The study will include 18 to 24 patients who have been healed early in the last three years. Women will receive three doses of the vaccine, each 14 days apart from the previous one.

Researchers will initially administer small doses of the vaccine to a few patients and monitor them closely. Only when they are sure it is safe will they include more participants in the study.

1. The editorial board recommends: Is it cancer already? These symptoms should give you food for thought

The clinical phase is expected to end in September 2022. The study brings hope not only to patients with triple-negative breast cancer. Scientists have set themselves the goal of using vaccines to treat other cancers as well.

Triple negative breast cancer – what is it?

Triple negative breast cancer affects 12 to 15 percent. all breast cancer patients. It is very aggressive and highly lethal. One quarter of patients die within five years of diagnosis. This type of breast cancer most often affects women with the BRCA1 mutation and African American women.

Unfortunately, the prognosis for triple-negative breast cancer is not good. This subtype of cancer grows rapidly, metastasizes, and patients are at risk of relapsing. The vaccine that protects against triple-negative breast cancer is therefore a preparation that may turn out to be an oncological breakthrough, saving many lives.

Have you had any cases of breast or ovarian cancer in your family? Are you worried that you may be a carrier of the BRCA1 gene mutation? Perform BRCA1 and BRCA2 genetic tests and find out if you are at risk.

Also read:

1. How to detect breast cancer at the earliest stage?
2. Cancer doesn’t have to mean breast loss
3. Breast cancer – what can I do to reduce my risk?

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