Used in post-traumatic pain in muscles and joints (sprains, sprains, bruises), back pain, pains in osteoarthritis and rheumatoid arthritis.
Tarproxen (Polfa Tarchomin)
| form, dose, packaging | availability category | the active substance |
| gel 0,1 g / g (10%) (30 g) | OTC (over-the-counter) | naproxen |
ACTION
Non-steroidal anti-inflammatory drug, propionic acid derivative
INDICATIONS AND DOSAGE
Post-traumatic pain in muscles and joints (sprains, sprains, bruises), back pain, pain in osteoarthritis and rheumatoid arthritis. 5 cm long gel strip (approx. 100 mg of naproxen) should be rubbed into the painful areas 4–5 × / d. The maximum topical dose is 500 mg (approx. 25 cm of a gel strip).
CONTRAINDICATIONS
Hypersensitivity to any component of the preparation or other non-steroidal anti-inflammatory drugs, 2rd trimester of pregnancy, breastfeeding, allergic skin diseases, inflammatory skin changes. Do not use under an occlusive dressing or on damaged skin. During treatment and XNUMX weeks after its completion, avoid exposure to sunlight (including solarium).
WARNINGS
Preparation for external use on the skin. Do not use on mucous membranes, damaged skin or in case of skin inflammation; avoid contact of the preparation with the eyes; if the preparation gets into the eyes, rinse them with plenty of water. Treatment should be discontinued in the event of an allergic reaction or skin lesions. Use with caution: in people who have a history of allergic reactions (eg rash, itching) to non-steroidal anti-inflammatory drugs; in people with liver or kidney failure; in people with gastric ulcer and / or duodenal ulcer; with blood coagulation disorders; with extreme heart failure and in elderly patients. Long-term use on large areas of the skin surface should be avoided because there is a risk of systemic side effects characteristic of non-steroidal anti-inflammatory drugs; in the event of their occurrence, the use of the preparation should be discontinued. Due to the content of propylene glycol, the preparation may cause skin irritation. It is not recommended for use in women in the first and second trimester of pregnancy. Use in the first and second trimesters of pregnancy only after consulting a doctor, when, in the doctor’s opinion, the benefit for the mother outweighs the potential risk for the fetus. Use in the third trimester of pregnancy and breastfeeding is contraindicated. There are no data on the effect of the preparation on the ability to drive vehicles.
INTERACTIONS
Naproxen applied topically to the skin may enter the bloodstream and react with drugs administered orally. May enhance the effects of anticoagulants, sulfonamides, oral antidiabetic drugs (sulfonylureas), acetylsalicylic acid and other non-steroidal anti-inflammatory drugs; may intensify the side effects of other non-steroidal anti-inflammatory drugs, alcohol, phenytoin, valproic acid derivatives, hydantoin and the toxic effects of methotrexate, lithium salts, digoxin, and aminoglycosides. Naproxen may reduce the effect of antihypertensive drugs, furosemide and increase the risk of ion disturbances. Probenecid increases the concentration of naproxen in the blood. Naproxen may interfere with adrenal function tests.
SIDE EFFECTS
The following may occur: local skin irritation, itching, rash, hives, redness, photosensitivity reactions, severe allergic reactions (difficulty breathing, coughing attacks, swelling of the face, shortness of breath), palpitations. After long-term use on large surfaces, possible side effects resulting from the general effects of naproxen (nausea, vomiting, constipation, diarrhea, exacerbation of gastric ulcer, jaundice, renal dysfunction, drowsiness, headache, tinnitus, visual disturbances, hypersensitivity reactions).