Symptoms of the disease

Symptoms appear in seizures:

• benefits abdominal cramps painful, especially in the lower abdomen;
• Du blood in stool (even hemorrhage in the event of a severe attack);
• Chronic diarrhea;
• benefits frequent bowel movements, even During the night;
• Un urgent need to defecateeven if there is little or no stool to pass (rectal tenesmus);
• A weight loss due to reduced appetite and poor absorption of nutrients in the intestine;
• From the almost complete fatigue, often caused by anemia;
• From the almost complete fever, especially in the case of pancolitis with significant symptoms;
• In children, severe ulcerative colitis can interfere with Development (growth retardation, puberty delay…).

People at risk

• Some populations are more at risk than others, due to thetheir genetic heritage. Whites are 2-5 times more affected by ulcerative colitis than blacks or Asians. The Jewish community (of Ashkenazi origin), for its part, is 4 to 5 times more affected by this disease than other populations.41,42;
• Up to 20% of people with ulcerative colitis have a loved one affected by Crohn’s disease or only 6% by ulcerative colitis, suggesting the existence of a genetic predisposition. If two parents are affected; the risk of occurrence of IBD in the lifetime is 36%

Risk factors

There are none known

• Living in a environment urban or in an industrialized country increases the risk of suffering from ulcerative colitis;
• Nonsteroidal anti-inflammatory drugs (NSAIDs, anti-inflammatory drugs other than corticosteroids) and oral contraceptives could be incriminated but this remains to be confirmed. NSAIDs are not recommended in cases of UC;
• Dietary factors are incriminated insofar as this disease mainly affects the countries of Europe and North America. (High consumption of sugar, red meat). The disease is increasingly affecting the Maghreb, which reinforces the role of food. (modification of diet in young people, soda, cola);
• Isotretinoin (Accutane), a medicine used in the treatment ofacne serious could sometimes be involved in the onset of certain ulcerative colitis. Even though the cause and effect relationship has not been proven, studies report cases of ulcerative colitis following the use of isotretinoin^{45, 46}.