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Sunburn and immunity: what happens while lying on the beach
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Why has sunbathing become harmful? What new scientists will tell us?
Now there are whole lines of effective protective agents that solve the problem of the harmful effects of UV rays on the skin. But how to prevent the consequences of its overheating? It is known that in the sun the upper layers of the skin can heat up to +40 ° C. Moreover, in this “overheated” state, they continue to be for many hours even after sunbathing. Why is thermal stress so dangerous?
What is leather and why do we need it
From the point of view of biology, the skin is a barrier tissue that separates the internal environment of the human body from the external one. Based on this, it is the skin, like no other tissue in our body, that experiences the effects of the environment. The nature of these effects is different: mechanical, chemical, temperature, etc. That is, in order to function as a barrier, the skin must simultaneously be mechanically strong, chemically and thermally resistant, must effectively protect us from ultraviolet rays and pathogens (viruses, bacteria) … Having solved all these problems, nature has created a very rational and beautiful design.
The basis of our skin is a special type of cells – keratinocytes. The life cycle of these cells is a sequence of transformations from a living cell into a keratinized scale. They form a multi-layered, complexly organized structure of tightly linked cells – the epithelium. The number of these layers determines the mechanical strength of the leather. The bottom layer is immature cells from which all the cells above the underlying layers originate. The upper layer of the skin is made up of numerous layers of already inanimate, keratinized cells. It is they who take on mechanical, physical and chemical influences, thus protecting living cells from them.
Protective cells against viruses and tumors
However, there are still many guest cells in the skin. For example, immunocytes. They grow and develop in the bone marrow, and then, traveling through the body, they also enter the skin. The environment in which these cells reside before being expelled into the skin is characterized by constant temperature and chemical composition. Here (in the skin) immunocytes are forced to share with the skin cells all the “hardships” of life in the periphery. When exposed to high and low temperatures, solar radiation, the functional state of such cells is seriously tested.
Among the immune cells of the skin there is a special type of cells – natural killer cells (NK cells). They perform a very important function – they recognize and kill virus-infected and transformed (tumor) cells. Disturbances in the normal functioning of these cells lead to serious consequences: relapses of herpes, skin neoplasms (papillomas), etc. It turned out that even a simple temperature fluctuation can affect the work of NK cells (“defender cells”). Several studies have shown that a short-term increase in temperature to +39 ° C dramatically reduces the ability of NK cells to recognize and destroy target cells.
That is why it is difficult to overestimate the possibility of maintaining the functions of the NK cells of our skin, which now and then find themselves in such conditions.
The discovery made in St. Petersburg
In 2013, the American journal International immunopharmacology described the properties of the Allostatin® peptide, discovered by a group of scientists from St. Petersburg State University. Allostatin® is a selective stimulator of NK cells. Scientists have found that in the presence of Allostatin®, NK cells detect and destroy 5 times more target cells.
Thus, Allostatin® can become a serious support for NK cells under changing temperatures. The first cosmetic product based on Allostatin® was a hydrogel for skin and lip care – Allomedin®.
Modern approaches to maintaining healthy skin include following the rules of post-tanning. It is common practice to use a cream containing vitamin E to restore the skin after exposure to UV rays.
To reduce the harmful effects of high temperatures on the skin, include Allomedin® gel in your usual post-care routine. The gel should be applied after a shower, to areas of the skin exposed to intense (excessive) sun exposure. It is not difficult to define them: firstly, these are always open areas of the body (face), and besides, such skin continues to “burn” even a few hours after exposure to the sun. The peptide gel Allomedin® quickly cools the skin, relieves pain and restores the work of “protective cells” without leaving any residue. Remember that a proper tan is a guarantee of beauty and youth for years to come.
* If signs of herpes have already appeared, apply Allomedin® every time you feel tingling, itching and burning.
Contact details:
Biotechnological company “Allopharm”
+7 (812) 320-55-42,
Contraindications are possible. Consult a specialist.