Still’s disease – what exactly does it mean and who is at risk of it?

Still’s disease is defined as a connective tissue disease, i.e. inflammation of the joints of any course. It is accompanied by symptoms similar to the flu, e.g. fever, muscle and joint pain, rash, enlarged lymph nodes and spleen. It is a rare disease that occurs most often at an early age – from 16 to 35 years of age.

What are the causes of Still’s disease?

It’s hard to say what is causing the main problem Still’s disease. Some viruses contribute to this, e.g. rubella, mumps, orphan viruses. Still’s disease it associates with the HLA-DR2, HLA-DR4, KLA-DR7 and KLA-B17, HLA-B18, HLA-B35 antigens.

Symptoms of Still’s disease

Choroba Still it may be permanent or recurrent – it is difficult to predict the frequency of relapses. About the chronic form korody Quiet we say when the symptoms last 12 months.

In the course of this condition, joint damage occurs, which often recurs later in life. There are two stages of the course korody Quiet: distinguished by chronic arthritis and distinguished by fever and difficult relapses. In adults Still’s disease it’s hard to recognize, but it’s done according to Yamaguci’s classification. There are large criteria in this classification: high fever, two-week joint pain, high level of leukocytes. Small criteria: sore throat, enlarged lymph nodes, negative for antinuclear antibodies. To the main symptoms korody Quiet these include: high fever, symptoms of pharyngitis, skin rash and itching, pain in joints and muscles.

W Still’s disease There may also be less frequent symptoms such as: hair loss, weight loss, enlarged lymph nodes, liver and spleen, respiratory or cardiovascular problems, even hearing or vision problems.

How is Still’s disease diagnosed?

Still’s disease is diagnosed on the basis of laboratory tests of blood serum – on this basis, the level of inflammatory indicators is determined. The synovial fluid is also collected, imaging tests are performed – X-ray (X-ray), computed tomography (CT).

How can Still’s disease be treated?

On an acute course korody Quiet treatment requires the use of non-steroidal anti-inflammatory drugs. If there is no improvement, glucocorticosteroids (GCS) are started. Especially if Still’s disease it will develop more and there will be inflammation of the heart muscle or liver damage.

In the chronic treatment of the disease, methotrexate is used, and in cases not eligible for treatment – TNF and IL-6 inhibitors.

Regardless of the intensity korody Quietrehabilitation treatment should be started at its initial stage. The prognosis depends on the course of the disease, but if large joints are affected by inflammation, it will not be the best.

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