Sorbifer durules – indications, contraindications, action, dosage

Proven content

Sorbifer Durules is used to treat both adults and children over 12 years of age. The indications for use may be the treatment of iron deficiency anemia or the treatment of latent iron deficiency. Sorbifer Durules can also be used for prophylaxis during pregnancy and during breastfeeding, taking doses prescribed by a doctor.

Sorbifer Durules – what is this drug?

Sorbifer Durules is a drug containing iron and vitamin C. It is available in the form of tablets – 1 tablet contains 100 mg of iron ions and 60 mg of ascorbic acid. In addition to them, it also contains auxiliary substances, such as: povidone k-25, polyethylene powder, magnesium stearate, carbomer 934 P. The shell includes, among others: hypromellose, solid paraffin, magnesium dioxide.

Thanks to the content of iron sulphate and ascorbic acid, Sorbifer Durules is helpful in the treatment of the following ailments:

1. Iron deficiency anemia is a subtype of anemia with one of the main causes of blood loss, for example during heavy menstruation, from trauma, and in multiple blood donors. An increased need for iron also occurs in pregnant and lactating women, in adolescence and during the treatment of vitamin B12 deficiency.
2. Latent iron deficiency – this is a state in which the body does not have iron reserves, but has enough of it to meet the current needs. In people with latent iron deficiency, the concentration of ferritin in the blood also decreases.
3. Iron deficiency during pregnancy – The need for iron in pregnant women increases by half. Thanks to it, the development of the child’s immune system is possible. Iron deficiency can cause developmental problems in a child, cause anemia, memory impairment, and reduce physical performance and concentration. It can also cause premature birth.

Sorbifer Durules – contraindications

Contraindications to use the drug Sorbifer Durules may be:

1. allergic to iron sulfate, ascorbic acid or any of the other ingredients of this medicine,
2. narrowing of the esophagus or other disorders that obstruct the movement of food in the digestive tract,
3. excessive amounts of iron in the body (hemochromatosis, hemosiderosis),
4. anemia not caused by iron deficiency,
5. multiple blood transfusions.

prepared Sorbifer Durules should not be used simultaneously with antibiotics (antibacterial drugs) belonging to the fluoroquinolone group (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin), with mycophenolate mofetil, immunosuppressants, antibiotics from the group of tetracyclinetracycin (e.g. ).

It should, however You should be particularly careful when it is necessary to use the preparation at the same time Sorbifer Durules z:

1. antacids containing aluminum hydroxide, magnesium carbonate,
2. captopril (a medicine to lower blood pressure),
3. drugs used in the treatment of bone disorders from the bisphosphonate group, such as: alendronate, clodronate, risedronate,
4. thyroid hormones (thyroxine),
5. penicillamine (a medicine that binds metals in the body)
6. Medicines to help treat Parkinson’s disease (for example, levodopa)
7. antihypertensive drugs containing methyldopa.

Sorbifer Durules – how to take the drug?

Before taking the first dose of the drug, consult your doctor or pharmacist. The tablet should be swallowed and washed down with water – this is the only correct way to use the medicine. The tablet should not be crushed, chewed, sucked or held in the mouth. The time of taking Sorbifer Durules is an individual matter and depends on gastrointestinal tolerance, but usually the drug should be taken before or during a meal.

Children over 12 years of age should take 1 tablet of the drug twice a day. When it turns out that the preparation causes side effects, the dose can be reduced by half. The dose can also be increased to 3 or 4 tablets – for example in the treatment of iron deficiency anemia. The preparation should not be given to children under 12 years of age and infants.

In the event of an overdose, consult a doctor immediately or go to the nearest hospital. An overdose of the drug in adults is not always as dangerous as in the case of young children. Take the drug regularly and do not double the dose if you have missed the daily dose.

Sorbifer Durules – interactions with other drugs

The manufacturer of the drug in the leaflet attached to the preparation suggests avoiding the combination of Sorbifer Durules with: ciprofloxacin, levofloxacin, moxifloxacin, mycophenolate mofetil, norfloxacin, ofloxacin. Combining the drug with incl. antacids, captopril, clodronate and thyroid hormones may require dose adjustment.

Preparations containing iron form complex compounds with alendronate – this is what in vitro studies have shown. Therefore, it is not advisable to combine them. By combining iron products with thyroxine, the latter component will be less absorbed, which will result in the ineffectiveness of substitution treatment.

What role does iron play in the body?

Iron is essential for the body to function properly. However, this mineral is not produced naturally, so it should be provided with food. When iron enters the body, it is then absorbed by the duodenum. Later, it combines with transferrin, where it goes to the liver, spleen and bone marrow. We distinguish heme iron and non-heme iron – the former is found in animal products and the latter in plant products.

The human body contains about 5 grams of iron, most of which is in hemoglobin. The iron contained in the bone marrow is involved in the formation of erythrocytes, i.e. red blood cells. The component is also found in the muscles and allows them to take oxygen from the blood. It is also found in tissue enzymes and affects cholesterol metabolism and enables detoxification in the liver.

What are the symptoms of an iron deficiency?

1. weakness,
2. somnolence,
3. apathy,
4. pale skin,
5. headaches,
6. dark circles under eyes,
7. quick fatigue,
8. increased heart rate
9. mouth corners,
10. weakening of the hair,
11. pale conjunctiva.

What are the symptoms of excess iron?

Contrary to appearances, excess iron in the body is not good for health. Sometimes the cause of this condition is eating too much red meat containing heme iron or overdosing on dietary supplements containing iron. Symptoms of excess iron in the body are:

1. stomach pain,
2. constipation
3. arthralgia,
4. hormonal disorders.

When does the body need more iron?

The greatest demand for iron occurs in girls during adolescence. It is also necessary in overweight people on reduction diets, vegetarians and postmenopausal women. Iron supplementation is also needed for women who have heavy periods and pregnant women. Pregnant women should also take care of regular iron intake – iron, like folic acid, are essential for the proper development of the baby’s nervous system.

Which foods contain the most iron?

One of the foods rich in iron is the liver, which contains about 20 mg of iron per 100 g – this is the amount of the element found in poultry, beef and pork liver. Iron is also rich in lean beef and pork, which contain about 3 mg of iron per 100 g. Other such products are eggs containing 4 mg of iron in 100 g, grain products, in particular rice bran, wheat bran, fish and fruit ( apricots, apples, blueberries) and vegetables (potatoes, parsley, spinach).

How to treat iron deficiency?

The most important step in correcting iron deficiencies is to remove the cause of their occurrence. If the process of iron absorption is normal in a given person, then a frequently used method of pharmacological treatment of this ailment is the use of iron-containing preparations such as, for example, Sorbifer Duruls. On the other hand, when a sick person does not tolerate oral preparations or, for various reasons, cannot absorb iron from the gastrointestinal tract, then he or she receives the ingredient parenterally.