Def .: Bone formation within the skin.
Etiol .: There are two types of ossification: primary, which is extremely rare – of unknown cause, and secondary ossification due to chronic inflammation, scarring after skin injuries. It has been suggested that ossification of the skin is the result of a disturbed differentiation of fibroblasts towards osteocyte precursors.
Local: In any location.
Clinical: Hard nodules, intradermal bone plates, sometimes the lesions are very painful.
Hist .: Bone tissue in the skin is often accompanied by an increase in adipose tissue or hematopoietic elements.
Heal: Surgical removal of lesions.
Year: Dependent on ossification type, good for localized secondary ossification.
Lit .: [1] Braun-Falco O., Plewig G., Wolff HH, Burgdorf WHC: Dermatology, eds. pol Gliński W., Wolska H., Wydawnictwo Czelej, Lublin 2004, 1495. [2] Czarniawska-Grzesińska M., Stępień B., Pietrzykowska-Fryca K .: Post Dermatol Alergol 2006, 23/5; 239-43. [3] Elder DE, Elentisas R., Johnson B. Jr. et al: Levers histopathology of the skin. Lippincott Williams & Wilkins, Baltimore 2007, 395.
Source: A. Kaszuba, Z. Adamski: “Lexicon of dermatology”; XNUMXst edition, Czelej Publishing House