Skin leukemia
Epid .: Skin lesions are more common in patients
with acute myeloid leukemia than lymphoblastic leukemia, in leukemias
chronic, and more often in the lymphatic form.
Etiol .: Peripheral blood leukemia cells penetrate the skin where they can persist for longer periods.
Lock: Eyelids, scrotum and areas with mechanical injuries. Infiltrates on the gums and tonsils are a common symptom of acute leukemia. In chronic lymphocytic leukemia, changes can occur on the face, giving it the characteristic appearance of a lion (facies leonina). Sometimes there is an increase in the nail folds or the subcutaneous tissue.
Clinical: Typical eruptions are in the form of lumps and nodules of cohesive consistency, domed shape, well-delimited edges, violet or reddish-brown in color. On their surface, ulcers are often found, and less often – blisters. Within the oral mucosa, leukemic infiltrates grow above the teeth and may even cover their crowns. They often cause bleeding gums and a stench from the mouth; they are often ulcerated and painful. Sometimes teeth fall out. Also, infiltrates within the tonsils can be painful and cause bleeding.
Hist .: Clusters of tumor cells, initially around blood vessels.
DR: Langerhans cell histiocytosis, Kaposi’s sarcoma, lymphoma, mastocytosis, sarcoidosis.
But., Rok .: Dependent on the form of leukemia.
Source: A. Kaszuba, Z. Adamski: “Lexicon of dermatology”; XNUMXst edition, Czelej Publishing House