Sialidoza

Syn .: Mucolipidosis type I, Springer syndrome.

Def .: The form of glycoprotein neuraminidase deficiency with the mildest clinical course and autosomal recessive inheritance.

Etiol .: Deficiency? α-neuraminidases with oligosaccharide storage.

Clinical: Multifocal ossification disorders, myoclonic spasms and mental development retardation are observed in patients. There are cornea of ​​the torso and the skin of the face is rough.

DL: Showing a deficiency? α-neuraminidase.

DR: Other lysosomal storage disorders.

Treat: Symptomatic.

Source: A. Kaszuba, Z. Adamski: “Lexicon of dermatology”; XNUMXst edition, Czelej Publishing House

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