How to live to be a hundred years old? Scientists have always been looking for an answer to this question. There are more research results that may bring us closer to solving the mystery of longevity. Centenarians have unique gut bacteria that stop the growth of more dangerous disease-causing bacteria, Japanese researchers have revealed.
Odoribacteraceae is a gram-negative family of bacteria that produces unique bile acids, thereby preventing the growth of other dangerous bacteria. Experts have found more Odoribacteraceae in people who have reached the age of one hundred. Are these bacteria in the body the secret of longevity?
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Research on centipedes – bile acid and age
Research published in the scientific journal “Nature” suggests that people who have reached the age of one hundred years can thank for their long life … intestinal bacteria, and more precisely, their increased number in the intestines.
However, Japanese scientists are not yet sure why this is so. The question of whether Odoribacteraceae are acquired more with age, or whether people with more of them already live longer earlier, remains open for now.
“Genetic factors and diet may have influenced the composition of the gut microflora,” study author Professor Kenya Honda of Keio University School of Medicine in Tokyo told Mail Online.
For the purposes of the study, experts analyzed the microbiome (all microorganisms present in a given habitat – ed.) Of centenarians on the basis of stool samples. To investigate the potential relationship between microflora composition and longevity, researchers studied three groups of Japanese people, 160 in total. Some of them were 100 years old, the second group consisted of people aged 85 to 89. Younger people aged 21 to 55 were also examined.
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From the samples, scientists found that centenarians had many more of the friendly Odoribacteraceae in their intestines than younger people.
Bile acid, known as isoallolytocholic acid (isoalloLCA), has been shown to have antibacterial activity against many intestinal pathogens. The results suggest that there is a link between longer life and bile acid-producing bacteria.
However, more research is needed to confirm the link between bile acids and longevity.
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