Rolicyn – indications, contraindications, dosage, side effects of an antibacterial drug

Rolicyn is an antibacterial drug for systemic use. Macrolide antibiotic used to treat bacterial infections. It is recommended as a treatment for nasopharyngitis, sinusitis, middle ear infections and infections of the skin and soft tissues. The preparation is available over the counter in the form of tablets.

Rolicyn, Producer: Polfa Tarchomin

Indications for taking the drug Rolicyn

Rolicyn is indicated for the treatment of the following infections caused by microorganisms sensitive to roxithromycin:

1. upper respiratory tract infections: tonsillitis, pharyngitis, nasopharyngitis,
2. sinusitis of the nose,
3. otitis media
4. lower respiratory tract infections: pneumonia, bronchitis, lung abscesses and bronchiectasis,
5. skin and soft tissue infections,
6. non-gonococcal infection of the reproductive organs caused by chlamydia, mycoplasma or ureaplasma.

Rolicyn and contraindications

Contraindications to the use of Rolicyn are:

1. hypersensitivity to any component of the preparation or to other macrolide antibiotics.
2. During treatment with roxithromycin, any of the following preparations are contraindicated: astemizole, cisapride, pimozide, terfenadine, ergot alkaloids (ergotamine or dihydroergotamine).

Dosage

1. Adults and children weighing more than 40 kg: 150 mg twice a day (every 2 hours) or 12 mg once a day.

No dosage adjustment is necessary in elderly patients with normal renal function.

1. Children weighing 12-40 kg: 2,5-4 mg / kg body weight twice a day.
2. Usually in children weighing 12-23 kg: 50 mg twice a day (every 2 hours) and in children weighing 12-24 kg: 40 mg twice a day (every 100 hours).

The use of Rolicyn is not recommended in people with severe hepatic insufficiency (e.g. cirrhosis of the liver with jaundice and / or ascites). However, if the doctor considers the use of the preparation necessary, then he or she will recommend a suitable dose reduction and regular monitoring of liver function parameters. If liver function deteriorates, the doctor will consider discontinuing the preparation.

Liver function parameters should also be regularly monitored in people with liver dysfunction and in those who have had liver problems in the past in connection with the use of macrolide antibiotics.

No dosage adjustment is necessary in people with renal insufficiency.

Rolicyn film-coated tablets should be swallowed whole (do not chew or break) with water. The tablets should be taken 30 minutes before a meal.

Rolicyn – warnings

1. There is no information that Rolicyn affects the ability to drive and use machines.
2. Do not use the drug in people with severe liver failure.
3. Pregnant women may only take this medicine when the doctor considers it absolutely necessary.
4. An allergic reaction may occur when using Rolicyn, then you should consult your doctor.
5. Concomitant use with ergot alkaloids (such as ergotamine or dihydroergotamine) is contraindicated as there is a risk of ergot poisoning manifested by peripheral vasospasm and limb ischemia (limb necrosis may occur) and central nervous system ischaemia.

Rolicyn with other drugs

Inform your doctor about taking the following preparations:

1. benzodiazepine derivatives (e.g. midazolam, alprazolam, trazolam),
2. cyclosporine and bromocriptine,
3. anticoagulants, such as warfarin, acenocoumarol, phenprocoumon
4. theophylline,
5. ergot alkaloids (ergotamine, dihydroergotamine),
6. astemizol, cyzapryd, pimozyd, terfenadyna,
7. drugs that can prolong the QT interval on the ECG (including antiarrhythmic drugs such as disopyramide, quinidine, procainamide, amiodarone),
8. digoxin and other cardiac glycosides.

Rolicyn – possible side effects

While taking Rolicyn, the following may occur: increase in liver enzymes or increase in bilirubin levels, cholestatic, or less frequently acute hepatitis, sometimes with jaundice, pancreatitis, headache and dizziness, digestive disorders, anorexia, pseudomembranous enteritis (manifested, among others, with diarrhea), bronchospasm , bronchial asthma, anaphylactic shock.