Ranigast Pro for heartburn and indigestion. Composition, dosage, recommended precautions

Ranigast Pro is a drug used in heartburn, indigestion without organic disease of the digestive tract (symptomatic treatment). The active substance in this medicine is ranitidine, which blocks the histamine type 2 receptors (H2 receptors) in the parietal cells in the stomach lining. The preparation is designed to inhibit the secretion of hydrochloric acid in the gastric juice. The drug is in the form of tablets and is available without a prescription.

Ranigast Pro (Polpharma)

ACTION

H2 receptor antagonist

Ranigast Pro – indications and dosage

Ranigast Pro is a drug recommended for the treatment of:

1. heartburn
2. indigestion without organic disease of the digestive tract.

Drug dosage

Ranigast Pro is in the form of film-coated tablets to be taken orally. Swallow the tablets whole with a drink of water. You can take the drug with or without food.

1. Adults and children over 16 years of age Orally; 75 mg, in case of persistent or recurring symptoms, the dose may be repeated after 1 hour;
2. dose max. 150 mg / day. Do not use for more than 2 weeks.

Ranigast Pro and contraindications

There are the following contraindications to the use of the drug:

1. allergy to any component of the preparation,
2. use in children up to the age of 16.

Ranigast Pro – warnings

1. Treatment with the drug may mask the symptoms of stomach cancer and cause a diagnosis that is too late.
2. Patients with renal insufficiency should reduce the daily dose as ranitidine is mainly excreted by the kidneys.
3. Patients with hepatic insufficiency should be careful as ranitidine is metabolised in the liver.
4. People taking non-steroidal anti-inflammatory drugs and ranitidine at the same time should be systematically monitored. Especially elderly patients with a history of peptic ulcer disease.
5. Ranitidine can cause acute porphyria attacks, therefore patients with a history of acute porphyria should not take the drug.
6. Elderly, diabetic, and immunocompromised patients are at increased risk of developing pneumonia.
7. This medicine contains sunset yellow, which may cause allergic reactions.
8. Pregnant and breastfeeding women may take the drug only after consulting a doctor and if necessary.
9. Patients driving motor vehicles should be careful, because the preparation may cause side effects in the form of dizziness and headaches or blurred vision, which may affect the ability to concentrate on the road.

Ranigast Pro with other drugs

1. Ranitidine contained in the preparation enhances the effect of preparations inactivated by this enzyme, such as: amoxicillin, diazepam, lidocaine, phenytoin, metronidazole, propranolol, theophylline and warfarin.
2. The absorption of ranitidine may be reduced when coadministered with moderate and severe antacids. Such medications should be taken at least one hour before or after administration of ranitidine.
3. Simultaneous intake of high doses of sucralfate (2 g) reduces the absorption of ranitidine. Absorption of sucralfate 2 hours after ranitidine did not affect its absorption.
4. There is no information on the interaction of interranitidine with amoxicillin or metronidazole.
5. Ranitidine contained in the drug may reduce the absorption of ketoconazole and other preparations, the absorption of which depends on the acidity of the gastric juice.
6. Cigarette smoking lowers the effectiveness of ranitidine.

Ranigast Pro – side effects

Taking Ranigast Pro may cause, among other things:

hypersensitivity reactions:

1. skin rash
2. hives
3. angioedema
4. fever,
5. bronchospasm
6. hypotension and chest pain
7. anaphylactic shock,

and:

1. transient changes in liver enzymes
2. usually transient haematological disturbances such as low white blood cell count (leukopenia) and thrombocytopenia,
3. agranulocytosis or pancytopenia, sometimes with bone marrow hypoplasia or aplasia,
4. transient states of confusion
5. depression and hallucinations (especially in seriously ill or elderly patients),
6. headaches (sometimes severe)
7. dizziness.