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Prohormones are compounds from which or under the influence of which hormones are formed. The term is used in two senses. In biological terms, they are hormone precursor molecules from which the proper hormone molecules are formed as a result of enzymatic modification. The term usually refers to peptide hormone precursors. A prohormone is, for example, vitamin D3, which produces the hormone calcitriol.
In the commonly used sense prohormony are substances used in sports support. These are drugs taken orally and influencing anabolic processes.
Natural prohormones are natural anabolic substances, which include such substances as: phytosterols, flavones, isoflavones, triterpene saponins, sterodium saponins, buteines, amino acid derivatives and ursolic acid. Tribulus terrestris extract is very often used, which is used in potency supplementation and the aforementioned increase in testosterone levels. Natural consumption, according to the producers prohormones leads to an increase in muscle mass, reduction of estrogen and reduction of body fat.
Prohormones for athletes
Prohormony in popular terms, they are synthetic chemicals that lead to an increase in muscle mass. Deadline prohormony it is most often present in sport, especially bodybuilding, as an alternative to illegal steroid hormones. Task prohormones is to stimulate the hormones present in the body. Prohormony first of all, they convert with testosterone, which has a great impact on anabolic processes, endurance and fat burning processes.
The originator prohormones there was a chemist Patrick Arnold. They were introduced to the dietary supplements market in 1996 as a cheaper and above all legal and safer version of banned anabolic steroids.
The most famous on the market prohormonami contained in supplements are:
- androstendion,
- 4-androstendiol,
- 5-androstendiol,
- 19-norandrostendion,
- 19-norandrostendiol.
The most commonly used prohormone jest androstendion, which turns into testosterone, and the effects of taking it are comparable to those of taking steroids.
Other target hormones they convert to prohormony:
- DHT (dihydrotestosterone) – a strong androgenic compound that influences the development of sexual characteristics. Larger amounts are found mainly in the genitals, prostate, skin, and brain. A positive effect is concentration, an increase in muscle hardness is noted. The side effect is acne as well as hair loss and prostate enlargement.
- Nandrolone – one of the most popular doping agents, used by competitors in competitive sports. Nandrolone is considered the safest steroid with the fewest side effects. It does not convert to DHT, but it works with estrogens, causing loss of libido, but it accelerates protein synthesis, increases mineralization and has a positive effect on bone growth.
- Boldenone – it is defined as a steroid of pure muscle mass. Boldenone stimulates the appetite, improves nitrogen balance, increases protein synthesis in muscle cells.
- 1-test (1-testosterone) is a very strong anabolic by 700%. more potent than testosterone and does not convert to estrogen. Consuming it accelerates regeneration, increases strength and muscle mass, and contributes significantly to the reduction of body fat. Unfortunately, it is also a very powerful androgen that causes acne and alopecia.
Prohormones – use
Prohormony are intended for people who want to increase strength and muscle mass. Prohormones should not be taken continuously, a 4-week break is recommended after two weeks of use. To achieve the desired effect, the intake of prohormones should be combined with a properly balanced diet rich in animal protein and active strength training.
Prohormones – side effects
ProhormonyLike any supplement introduced into the body, they can cause side effects, such as acne skin changes, enlargement of the breast tissue, hair loss leading to baldness. Receiving prohormones can damage the liver as it is mainly where metabolism takes place prohormoneswhich are hepatotoxic. In order to prevent damage to the liver, hepatic sheaths and general-protection preparations should be used to regenerate internal organs. Take prohormones in high doses for a long time as a result will reduce or completely stop the production of testosterone, because the body gets used to receiving hormones from the outside, which will disrupt the natural production of testosterone.
Prohormones – contraindications
Prohormones must not be administered to people under 25 years of age, because they strongly interfere with the hormonal balance that is still developing at this age and it may cause serious irreversible changes. To avoid prohormones women should especially, as these are male hormones and therefore may experience much greater negative side-reactions than men. He doesn’t give up prohormones in diseases of the liver, kidneys, heart diseases and diabetes.