Pre-neoplastic conditions of the mucosa – white keratosis, Bowen’s disease, Queyrat erythroplasia

Keratosis white

Syn .: Leukoplakia, smoker stain.

Def .: Leukoplakia is a precancerous condition.

Epid .: It more often affects men over 50 years of age.

Etiol .: It is not fully explained. The risk factors for leukoplaki are: tobacco, injuries, sun exposure, spicy foods, alcohol.

Lock: Tongue, lower lip and cheeks, labia majora, labia majora, obese groove, foreskin.

Varieties: flat and papillary.

Clinical: Whitish patches slowly transforming into hard discs with red clefts and erosions and an inflammatory reaction on the periphery of the lesions (Schwimmer’s limbus). Itching and burning are common.

DR .: Wilson’s lichen planus, lupus erythematosus, mucosal candidiasis.

Heal: Elimination of risk factors, mild non-irritating diet, treatment of comorbidities (vitamin deficiencies, syphilis). Vitamin A, B vitamins, PP are used; elimination of secondary inflammatory changes. Cytological and histopathological control of the eruptions. Surgical removal of lesions or cryotherapy.

Choroba Yourself

Syn.: Bowen’s disease.

Def .: Single or multiple, white papillary, brown eruptions on the mucosa, often with a hyperkeratotic surface, up to several cm in diameter. It is a precancerous condition.

Epid .: The disease most often affects the elderly over 60 years of age.

Etiol .: The risk factors are: age, sunlight, poisoning with inorganic arsenic compounds, HPV-16 – papillomavirus.

Lock: Mouth angles, lips and tongue, palate.

Hist .: Dysplasia of the epithelial spinous layer combined with cell atypia, leukocyte infiltration, epithelial icicles.

DR: Superficial basal cell carcinoma, atrophic and pigmentary lichen planus, long-standing psoriasis.

Treatment: Cryotherapy, laser therapy, surgical removal of lesions.

Queyrat erythroplasia

Syn.: Erythroplasia Queyrat.

Def .: Red hyperplastic lesion on the penis glans with a smooth, shiny surface. It is a precancerous condition.

Epid .: It occurs mainly in men.

Locale: Rarely occurs on the mucous membranes of the oral cavity – the fundus, lateral surfaces of the tongue, soft palate. The glans and foreskin, labia mucosa.

Clinical: Well-defined, smooth, red stain. Most often, the course is asymptomatic, although it may cause itching or burning.

DR .: Nonspecific inflammation of the glans in men, and the vulva in women.

Healing: Surgery, laser therapy, cryotherapy.

Source: A. Kaszuba, Z. Adamski “Practitioner’s guide. Dermatology”; XNUMXst edition, Wydawnictwo Czelej

Leave a Reply