Pills and medicines for urinary incontinence

Urinary incontinence is a serious problem faced by both men and women. It affects not only children, but also adults. Especially often urinary incontinence is observed in women, which is explained by the physiological characteristics of their body, as well as complications during labor. Self-medication does not bring the desired results, since the treatment of urinary incontinence requires an integrated approach. It is very difficult to manage without medical help. Only a doctor can find out the exact causes of urinary incontinence and prescribe drugs that will help to cope with the problem.

Medicines for urinary incontinence are selected based on the etiology of the disease. Therefore, consultation with a specialist is mandatory. In medical practice, stress and imperative urinary incontinence is most common. In the first case, urine flows out of the bladder due to weakness of the pelvic muscles and sphincter, and in the second case, the cause of its incontinence is the hyperactivity of the organ. Each condition requires correction with various drugs.

Table of essential drugs for urinary incontinence

Ovestin suppositories for urinary incontinence

Pharmacological properties. Ovestin suppositories contain the hormone estriol, so they are prescribed for the treatment of muscle atrophy of the genitourinary tract, which occurs against the background of hormonal imbalance (estrogen deficiency). The pharmacological effect of the drug is achieved due to the female hormone estriol, which restores the normal epithelium of the urethra and vagina, preventing the development of atrophic changes in the tissues. Most often, such disorders occur in women during menopause and after it.

Method of administration. Candles are administered intravaginally, before a night’s rest, in the supine position. For urinary incontinence, 1 suppository per day is prescribed for the first few weeks. The duration of use of the drug is determined by the doctor on an individual basis. Then the dose is reduced and administered 1 suppository 2 times a week.

Side effects:

• Itching and irritation in the vaginal area.

• Pain, hypersensitivity reactions – all these symptoms are observed when using impressive doses of the drug.

• Neoplasia (malignant and benign).

• Pulmonary embolism.

• Stroke and heart attack.

• Purpura of hemorrhagic type.

• Cholelithiasis.

• Chloasma.

• Alopecia.

• Erythema (nodular and multiform).

Reviews. Most women who have used Ovestin suppositories for urinary incontinence note their high effectiveness. The most common side effects they call the occurrence of a burning sensation in the vaginal area.

So, Ovestin suppositories can be used in the complex treatment of urinary incontinence, which is caused by a lack of estrogen in the body. However, the drug has many contraindications and side effects, so you can use it only after medical consultation.

Minirin

Mechanism of action. The drug Minirin has proven itself in the fight against enuresis in children. The composition of the drug contains a synthetic analogue of the hormone, which is produced by the back of the pituitary gland. The effect occurs already 15 minutes after taking the drug and lasts for 10 hours.

Contraindications:

• Polydipsia (congenital and psychogenic).

• Pathology of the heart.

• Obesity.

Features of treatment with Minirin:

• If there is no effect from the treatment, then the dose should be increased.

• The course of treatment, on average, is 3 months.

• The course, if necessary, can be repeated, taking a break of 7 days.

• Tablets are not washed down with water, do not drink liquid after taking the drug.

Reviews. Reviews about the use of the drug are most often positive. Parents call one of the advantages of the drug that children do not refuse to take the drug (it needs to be dissolved under the tongue), since the tablet has no taste. In addition, Minirin allows you to get rid of urinary incontinence even in cases where other drugs have been ineffective.

Separately, it is worth noting the high cost of the drug, but it is justified by the fact that the drug really works and eliminates an unwanted symptom. The effect is observed after a few days from the start of treatment. Parents indicate that relapses in children after a course of treatment do not occur.

As for side effects, they appear extremely rarely. Among the adverse events noted: headaches, abdominal pain, nausea. As a rule, Minirin is well tolerated.

Driptan

Driptan is a drug that comes in the form of tablets. The therapeutic effect is achieved due to the main active substance called “oxybutynin hydrochloride”.

Mechanism of action. The drug relaxes the detrusor of the bladder, thereby increasing its capacity. In parallel, the frequency of contraction of the walls of the organ decreases, the spasm is relieved, due to which the person does not have the urge to urinate with an incomplete bladder. The effect can be felt already 45 minutes after taking the drug.

Driptan is prescribed for the treatment of urge urinary incontinence in adults against the background of an overactive bladder, for the treatment of incontinence with cystitis, after undergoing bladder surgery. You can use Driptan for the treatment of enuresis in children against the background of unstable bladder function, with nocturnal enuresis, with idiopathic organ dysfunction.

Contraindications to the use of the drug:

• Age to 5 years.

• Increased body temperature.

• Ulcerative colitis.

• Obstruction of the urinary tract.

• Pregnancy and lactation.

• Myasthenia gravis.

• Gastroesophageal reflux.

• Diseases of the colon, colostomy, ielostomy, intestinal obstruction.

Since the drug has contraindications for use, it can not be prescribed independently. Take the drug only on the recommendation of a doctor who individually determines the dose for a particular patient. Average dosage: 1 tablet, 2-3 times a day for adults and 1/2 tablet 2 times a day for children.

Side effects. Possible disorders of the digestive system (vomiting, dry mouth, nausea), abdominal pain, disorders of the central nervous system (drowsiness, headache, etc.), visual disturbances, dysuria, urinary retention, tachycardia, arrhythmia, allergic reactions .

Reviews. If we consider the reviews, Driptan is quite well tolerated by both adults and children. However, it must be used correctly, without exceeding the dosage.

Patients treated with Driptan indicate its effectiveness in urinary incontinence. Some people have noted the appearance of pain in the abdomen, which disappear after discontinuation of the drug.

Picamilon

The mechanism of influence. Picamilon is prescribed for the treatment of urinary incontinence in children and adults. It has a positive effect on the functioning of the bladder, as it reduces detrusor hypoxia. Therefore, it is often prescribed in complex therapy for neurogenic bladder, with violations of the urodynamics of the urinary tract according to the hyperreflex type. Taking Picamilon improves the storage function of the bladder.

In addition, the effect of the drug is based on its ability to expand the vessels of the brain, to have an antioxidant, tranquilizing and psychostimulating effect. Due to the normalization of the functioning of the nervous system, it becomes easier for a person to restrain urges. Sleep will be better, but sensitive, which helps to avoid nighttime urine leaks.

Contraindications and side effects. It is forbidden to treat children under the age of 3 years with Picamilon, it is not prescribed for lactating and pregnant women, as well as against the background of kidney disease.

Side effects are very rare in both children and adults. Among them, allergic reactions, nausea, headaches, overexcitation, increased irritability are noted.

Reviews. Most of the reviews about this drug are positive. However, its effect on urinary incontinence is not always sufficient.

Duloxetine

Mechanism of action. Duloxetine is an antidepressant drug. It is recommended to use it with frequent urge to urinate, as it has a sedative effect and has a positive effect on the nervous regulation of the bladder. Also, the drug helps to relax the muscles of the organ, but the contraction of the muscle of its sphincter.

Duloxetine is recommended for stress urinary incontinence.

Side effects and contraindications:

• Insomnia and drowsiness.

• Dizziness.

• Vision problems.

• Trembling of hands.

• Decreased appetite.

• Increased fatigue.

• Dryness in the mouth.

• Constipation or diarrhea.

It is important to pay attention to contraindications to the use of this drug, including: glaucoma, breastfeeding, pregnancy, age under 18 years, renal and hepatic insufficiency, high blood pressure.

It should be taken into account that the abrupt withdrawal of the drug threatens with the occurrence of headaches, jumps in blood pressure, tachycardia and dizziness attacks.

Melipramine

Mechanism of action. Melipramine is an antidepressant that is also used as an antidiuretic. Its mechanism of action is based on reducing the depth of sleep, which makes it more responsive and enables a person to wake up when the bladder is full. The drug is available in injections for intramuscular injection, in capsules and tablets. For the treatment of enuresis, most often it is the tablet form of the drug that is prescribed.

Treatment of urinary incontinence with Melipramin can be started in children from 6 years of age. The duration of taking the drug is strictly limited by medical recommendations. Children under 6 years of age are not prescribed Melipramin.

How the drug is taken. The dosage is selected by the doctor. It is recommended to start therapy with minimal doses, increasing it if the desired effect is absent. Average dose: 1 tablet 1 time per day 30 minutes before bedtime. To calculate the dose more correctly, you need to know the patient’s weight. The calculation is based on the scheme: 1 mg of active ingredient per 1 kg of weight. The average duration of treatment is 2 months.

Side effects and contraindications. Do not prescribe Melipramin to people with diabetes mellitus, liver and kidney diseases, against the background of exacerbation of infectious diseases, with tuberculosis and heart pathologies.

As for side effects, the appearance of such undesirable manifestations as:

• Drop in blood pressure.

• Headache.

• Sleep disturbance.

• Urinary retention.

• Dryness in the mouth.

• Allergic reactions.

• Nausea and vomiting.

• Obesity.

Reviews. Most people who took Melipramine for urinary incontinence were satisfied with its effect. It will be noticeable after a few days from the start of therapy. However, it is important that the drug is prescribed by a doctor, since its independent use can only aggravate the existing problem. The price of Melipramine is very affordable, which is its undoubted advantage.

Pantocalcin

Mechanism of action. Pantocalcin is a nootropic drug that has a wide spectrum of action. It is an antagonist of GABA receptors, helps to eliminate autonomic disorders, increases the volume of the bladder, reduces the amount of urination, and eliminates imperative urges.

Dosage for urinary incontinence. Depending on the age of the patient, 25-50 mg of the drug is prescribed, 3 times a day. You need to take it in the morning and evening hours. The course of treatment is 60 days.

Side effects and contraindications. Side effects of the drug are extremely rare. At the same time, a positive trend is observed in most people suffering from urinary incontinence.

As for contraindications, Pantocalcin is not recommended for children under the age of 3 years, since it is available exclusively in the form of tablets. Other contraindications are pronounced disorders in the liver and kidneys.

Reviews. Reviews about the treatment with Pantocalcin are mostly only positive. A properly selected therapeutic course allows you to achieve a stable remission, or complete relief from urinary incontinence. If we consider the negative consequences of taking the drug, then among them we can distinguish increased irritability and excessive absent-mindedness. Although it has not been established that these effects were provoked by the intake of Pantocalcin.

Pantogam

The mechanism of action on the body. Pantogam is a nootropic drug that is prescribed in the treatment of urge urinary incontinence. The drug has a moderate sedative effect, stimulates the metabolism in neurons. The positive therapeutic effect of Pantogam in the treatment of secondary enuresis is explained by its vegetotropic activity, as well as the ability to influence the functions of the bladder sphincter. The conducted research allowed to establish that Pantogam allows to effectively correct the neurotic conditions that often accompany enuresis in childhood.

Features of the application:

• The dose of the drug is gradually increased over 10-20 days.

• Then the dose is gradually reduced over 10-20 days until completely canceled.

The course can be repeated 2-3 times a year.

The drug is prescribed for the treatment of urinary incontinence in children, adults and elderly patients. The average dose for an adult is 3 tablets per day. The drug is taken after meals. For children, there is such a dosage form as syrup, which is very convenient.

Contraindications and side effects. The drug is not prescribed during the first trimester of pregnancy, as well as for people suffering from severe kidney disease. As for side effects, they occur extremely rarely and come down to allergic skin rashes, rhinitis and conjunctivitis.

Batmiga

Betmiga is a drug for the treatment of urological diseases, in particular, urinary incontinence and OAB. The drug is produced in tablet form. One tablet of 25 mg or 50 mg contains 25,0 mg or 50,0 mg of mirabegron, which is the main active ingredient. Auxiliary components do not affect the course of the disease.

Mechanism of action. Taking the drug relaxes the smooth muscles lining the bladder. Its reception improves the reservoir function of the body, that is, it contributes to its normal performance: filling and evacuation.

Therapy with Betmiga most often does not affect the functioning of other body systems, but according to some reports, it can lead to a slight increase in heart rate and an increase in blood pressure. After discontinuation of the drug, all phenomena disappear.

Indications: hyperactive bladder, urinary incontinence, frequent urination, urgency.

Contraindications: allergy to the components that make up its composition, age under 18, breastfeeding, pregnancy, severe renal failure, high blood pressure.

Dosage. The daily dose for adult patients is 50 mg. It is accepted once. Features of nutrition do not matter. Wash down the tablets with water. They do not need to be chewed before use. Diseases of the kidneys and liver require dose adjustment. For such patients per day, it should not exceed 25 mg. The duration of therapy is determined by the doctor.

Side effects:

• Tachycardia;

• Urinary tract infections;

• Very rarely – atrial fibrillation;

• Puffiness of the eyelids;

• dizziness, headache;

• nausea, diarrhea, or constipation;

• Swelling of the joints.

Reviews. Most patients respond positively to Betmiga. They tolerate it well, they rarely experience adverse reactions. The main thing is to strictly observe the dose and not to combine tablets with incompatible substances.

Patients treated with Betmiga indicate a positive trend in the treatment of urinary incontinence. There is evidence of the development of tachycardia, but after discontinuation of the drug, this phenomenon disappears on its own.

Funds for urgent form

To eliminate bladder hyperactivity, anticholinergic drugs are prescribed, including: Novitropan, Driptan, Roliten, Uroflex, Urotol, Detruzitol. They act on the bladder detrusor. However, side effects after taking these drugs can be called such conditions of the body as: constipation, drowsiness and dizziness.

Such new generation drugs have a relaxing effect on the detrusor, such as:

• Vesikar (Solifenacin).

• Spasmex (trospium chloride).

• Toviaz (Fesoterodine).

• Mirobegron (Begming). This drug has a minimal set of side effects and can significantly increase bladder reserves.

Self-treatment of the urgent form of urinary incontinence with any drugs is unacceptable. During the passage of the therapeutic course, you should stop drinking alcohol.