It is used in pain of various origins of low and moderate intensity and fever.
Paracetamol Aflofarm (Aflofarm Pharmacy Poland)
| form, dose, packaging | availability category | the active substance |
| oral content 0,024 g / ml (0,12 g / 5 ml) (100 ml) | OTC (over-the-counter) | paracetamol (paracetamol) |
ACTION
Non-opioid drug with analgesic and antipyretic properties
INDICATIONS AND DOSAGE
Pains of various origins of low and moderate intensity, fever. Kids. Orally. 10-15 mg / kg bw once or depending on age: 3–12. months of age 60–120 mg, 2–6 months 120–240 mg, 7–12. years of age 240–480 mg. The dose can be repeated every 4 hours up to 4 times / day.
CONTRAINDICATIONS
Hypersensitivity to any component of the preparation, severe liver or kidney failure, viral hepatitis, alcoholism.
WARNINGS
Do not use for more than 10 days in adults and not more than 3 days in children without a doctor’s recommendation. In children up to 2 years of age, the preparation can be used only on the recommendation of a doctor. In order to avoid overdose, check that other taken preparations do not contain paracetamol. Do not exceed the recommended doses. Caution should be exercised when using the drug in patients with impaired liver or kidney function and in patients with bronchial asthma or allergic to acetylsalicylic acid. Do not drink alcohol during the treatment period due to the risk of toxic liver damage. People who are fasting and / or regularly drink alcohol are at particular risk of liver damage. In people with glucose-6-phosphate dehydrogenase deficiency, paracetamol may induce haemolysis of blood cells. Use of the preparation in pregnant and breastfeeding women only after consulting a doctor and only if absolutely necessary.
INTERACTIONS
Paracetamol enhances the effect of anticoagulants from the group of coumarin and indanedione derivatives. Salicylamide increases the elimination time of paracetamol. Do not use with MAO inhibitors or within 14 days from the end of treatment with these preparations due to the possibility of agitation and high fever. The use of drugs that increase hepatic metabolism, such as rifampicin, antiepileptic drugs (phenobarbital, phenytoin, carbamazepine), some sleeping pills or alcohol consumption may cause toxic liver damage, even when using the recommended doses of paracetamol. The use of paracetamol and non-steroidal anti-inflammatory drugs increases the risk of renal dysfunction. Paracetamol increases the toxic effect of zidovudine. Metoclopramide accelerates and propantheline delays the absorption of paracetamol. The use of paracetamol may affect the results of laboratory tests, for example, the determination of blood glucose or uric acid levels.
SIDE EFFECTS
The following may occur: nausea, vomiting, diarrhea, hepatomegaly, urticaria, erythema, rash, pruritus, angioedema, dyspnoea, sweating, hypotension, anaphylactic shock, bronchial asthma attack, renal colic, renal papillary necrosis, renal failure. Very rare: thrombocytopenia, agranulocytosis, methaemoglobinaemia. The most serious side effect may be acute liver injury, usually associated with overdose of paracetamol.