Pancreatic polypeptide is a peptide produced by PP cells of the dispersed endocrine system of the gastrointestinal tract.
PP cells are located mainly in the head of the pancreas. Nutrients stimulate peptide synthesis.
When do we do?
1. Differentiation of pancreatic diseases.
2. Suspicion of gastrointestinal neoplasm producing pancreatic polypeptide.
Test material: serum.
Preparation for the test: on an empty stomach (at least 8 hours).
The course of the study: one-time blood sampling from a vein in the arm.
Time to wait for the result: 1 Day.
Standard: less than 200 ng / ml.
Comments: The release of pancreatic peptide is increased after a meal is taken. Pancreatic polypeptide reduces pancreatic secretion, inhibits contractility of the gallbladder and stimulates gastric secretion, and also delays gastric emptying. It also influences the production of glycogen by the liver and plays a role in regulating intestinal motility. By stimulating the sympathetic nervous system, it increases energy expenditure.