Oral papillomatosis

Oral florid papillomatosis.

What is oral papillomatosis?

Oral papillomatosis is extensive papillary lesions of the mouth, less commonly of the pharynx, larynx or esophagus, considered a type of papillary cancer or a transient form between papillomas and papillary cancer. It is a rare disease (incidence in the USA – 1-3 per million people annually). The disease is more common in older men.

Causes of oral papillomatosis

Factors predisposing to the disease are

  1. HPV infection,
  2. smoking or chewing tobacco
  3. chewing betel nut
  4. chronic stomatitis.

Oral papillomatosis – symptoms

The lesions are most often located on the mucosa of the cheeks, gums or the hard palate. They resemble warty, non-ulcerative, painless chronic lesions. The changes gradually spread to an increasing area of ​​the oral cavity. Involvement of the tonsils and larynx is often observed.

How to treat oral papillomatosis?

Surgical removal is necessary, and if the extent of the lesions allows it, photodynamic therapy and laser therapy are used.

Prognosis: Chronic course, about 30% develop squamous cell carcinoma.

Lit.: [1] Schwartz R.A.: Verrucous carcinoma of the skin and mucosa. J Am Acad Dermatol 1995, 32; 1-21.

Source: A. Kaszuba, Z. Adamski: “Lexicon of dermatology”; XNUMXst edition, Czelej Publishing House

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