Syn .: Clear cell hidradenoma, acrospiroma eccrinale, nodular cystic sweat adenoma, clear cell myoepithelioma.
Def .: A benign tumor originating from the sweat glands.
Epid .: K: M like 1,7: 1; mean age 37,2 years.
Loc .: Head, face, upper limbs.
Clinical: Single solid or cystic nodule, flesh-colored, red to blue, 1-2 cm in size, although larger tumors have been reported. The changes show a slow steady growth. Pressure may be painful.
Hist .: Within the dermis, there are ductal structures and small cysts, the wall of which is made up of two types of cells: clear cells, eccrine cells with secretory capacity, and smaller basal-like cells.
DI: Cells show staining for 5/6/7 cytokeratin content characteristic of epithelia. Bright cells stain for 10/17/18 cytokeratins.
DR: In histopathological examination it resembles metastases of melanoma and clear cell tumor of the kidney.
Treatment: Surgical removal.
Year: Successful, recurrence possible in case of incomplete excision; the risk of malignancy of 6,7%.
Lit.: [1] Volmar K.E., Cummings T.J., Wang W.H. i wsp.: Clear cell hidradenoma: a mimic of metastatic clear cell tumors. Arch Pathol Lab Med 2005, 129(5); 113-6. [2] Storm C.A., Seykora J.T.: Cutaneous adnexal neoplasms. Am J Clin Pathol 2002, 118(Suppl. 1); 33-49.
Source: A. Kaszuba, Z. Adamski: “Lexicon of dermatology”; XNUMXst edition, Czelej Publishing House