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Nedal is a beta-blocker drug that reduces the heart rate and the force of its contraction, and lowers blood pressure.
Nedal – composition
The active substance of the preparation is nebivolol. It is a substance that belongs to a group of medicines called beta-blockers (another name used is beta-blockers).
Nedal – indications
The preparation is indicated in the treatment of essential arterial hypertension and chronic stable, mild or moderate heart failure, as an adjunct to standard treatment in elderly patients (over 70 years of age).
Nedal – action
Operation in detail He did not give the drug described in the leaflet attached to the medicine. Pharmacological blocking of beta receptors prevents their stimulation, and thus limits the effects of adrenaline or noradrenaline on target tissues with beta receptors. Adrenaline increases the heart rate and causes the peripheral blood vessels to contract. The action of Nedal, as well as of other medicines of this group, lowers the heart rate and the force of its contraction, and lowers blood pressure.. Lek Nedal it is selective for the beta 1 receptors in the heart, which reduces the risk of peripheral side effects (e.g. risk of narrowing of the airways due to blockade of beta 2 receptors in bronchial smooth muscle). Moreover He did not give the drug it has a slight peripheral vasodilating effect due to its influence on the synthesis of nitric oxide. The drug has very good opinions among doctors and patients, because the effects are noticeable very quickly (after a week from the start of the treatment).
Nedal – contraindications
The preparation cannot be usedif hepatic failure or impaired liver function, acute heart failure, cardiogenic shock, and in periods of worsening heart failure requiring intravenous inotropic drugs, when the patient has second or third degree atrioventricular block (in patients without a pacemaker), when suffers from sick sinus syndrome, including sinoatrial block, hypotension (systolic blood pressure below 90 mmHg), and also has bronchial asthma, bronchospasm or severe chronic obstructive pulmonary disease. The preparation must not be used during pregnancy, unless, in the doctor’s opinion, it is absolutely necessary. The preparation is contraindicated during breastfeeding.
The active substance nebivolol is also present, inter alia, in in the preparations of Nebilet, Ebivol, Daneb.
Nedal – dosage
After oral administration He did not give the drug it is quickly absorbed, and its bioavailability largely depends on the genetic determinants of its metabolic rate (the dose should be adjusted to the individual needs of the patient).
He did not give – the price
The price of the drug ranges from PLN 9,59 to PLN 11,59 for a package of 28 tablets (5 mg) coated.
Before use, read the leaflet, which contains indications, contraindications, data on side effects and dosage as well as information on the use of the medicinal product, or consult your doctor or pharmacist, as each drug used improperly is a threat to your life or health.