MIG for use in pain and fever. How many MIG tablets can you take per day?

Mig is a preparation used to relieve pain (mild, moderate) and fever. The preparation is in the form of coated tablets and is dispensed without a prescription. The active substance of the drug is ibuprofen, which has anti-inflammatory, analgesic and antipyretic properties. After taking the drug, this substance is quickly absorbed in the stomach and large intestine. Taking tablets is contraindicated in women in the third trimester of pregnancy.

MIG (Berlin-Chemie)

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Mig is a non-steroidal anti-inflammatory drug whose active ingredient is ibuprofen. The action of this substance is primarily the inhibition of the activity of cyclooxygenases (both COX-1 and COX-2). The drug reduces symptoms such as:

1. temperature,
2. pain,
3. edema.

Migration of indications and dosage

Mig is indicated for use in pain of various genesis and fever. The medicine is in the form of tablets and should be taken orally (whole) with or after a meal. Do not exceed the recommended daily dose. The dose of the preparation is based on body weight and age.

Dosage:

1. Adults. 200-400 mg once or every 6 h, max. 1,2 g / day.
2. Kids. 7-10 mg / kg once or every 6 h, max. 30 mg / kg b.w./d.

Mig contraindications for use

Contraindications to the use of the drug are:

1. hypersensitivity to any component of the preparation,
2. nonspecific haematopoietic disorders, active or recurrent gastric and / or duodenal ulcer disease,
3. gastrointestinal haemorrhage (two or more separate episodes of proven ulceration or bleeding)
4. gastrointestinal bleeding or perforation following a history of non-steroidal anti-inflammatory drugs
5. bleeding in the brain or other active bleeding
6. severe renal, hepatic or heart failure
7. III trimester of pregnancy.

Do not use:

1. in children <20 kg bw. under 6 years of age,
2. People who have developed bronchospasm, asthma, rhinitis or urticaria after taking acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.

Immediate medication alerts

1. Avoid using the drug in parallel with other non-steroidal anti-inflammatory drugs (including selective cyclooxygenase-2 inhibitors).
2. Take the preparation in the lowest possible dose for the shortest possible time.
3. The elderly are at risk of developing complications.
4. Gastrointestinal haemorrhage, ulceration and perforation may occur (may be fatal) while taking the drug.
5. Inform your doctor about any disturbing symptoms (e.g. bleeding) in the initial phase of taking the drug. This is especially true for the elderly and those with peptic ulcer diseases.
6. The use of low-dose acetylsalicylic acid also poses a risk of side effects (consult your doctor before taking this medicine).
7. Patients using oral medications (e.g. oral corticosteroids; anticoagulants such as warfarin; selective serotonin reuptake inhibitors antidepressants; antiplatelet agents such as acetylsalicylic acid) should be cautious as they may induce gastric ulcer and / or duodenum and bleeding.
8. Discontinue treatment with the preparation and consult a doctor if you experience gastrointestinal bleeding (tarry stools, bloody vomiting).
9. Crohn’s and Crohn’s exacerbations may occur while taking the drug.
10. People with hypertension should exercise caution (medications can cause fluid retention and increase blood pressure and swelling).
11. There is an increased risk of a heart attack or stroke when using the preparation in high doses (2400 mg per day).
12. The concomitant use of other painkillers may lead to renal failure.
13. In the event of nosebleeds, chest pain, convulsions, fainting, visual disturbances (scotomas, color vision disturbances), treatment should be discontinued and a doctor consulted.
14. Patients with lupus erythematosus and mixed connective tissue disease are at risk of developing meningitis.
15. Patients after surgery, with coagulation disorders, gastrointestinal diseases, Leśniowski and Crohn’s diseases, hypertension, allergic reactions, respiratory disorders, rhinitis and nasal polyps – should be careful and use the drug under strict medical supervision.
16. Liver, kidney and blood counts should be monitored during long-term use of the drug.
17. Patients taking the drug for an extended period of time are prone to headaches.
18. There is a risk of side effects when consuming alcohol.
19. The use of non-steroidal anti-inflammatory drugs by women may cause fertility problems.
20. Women in the first and second trimesters of pregnancy may use the drug only after medical consultation.
21. The use of the drug in the third trimester of pregnancy is prohibited.
22. During the breastfeeding period, use the drug only after medical consultation.
23. In people driving motor vehicles the following may occur (rarely): visual disturbances, dizziness and fatigue.

Mig and other medications

Avoid using Mig with the following medications:

1. acetylsalicylic acid or other non-steroidal anti-inflammatory drugs – increased risk of side effects,
2. diuretic or antihypertensive drugs – reduction of their effectiveness, deterioration of kidney function,
3. anticoagulants (possible increase in their effect, e.g. warfarin),
4. zidovudine – prolongation of the bleeding period,
5. phenytoin,
6. methotrexate and lithium – increases in plasma levels of both phenytoin and lithium and methotrexate should be monitored,
7. corticosteroids – gastrointestinal side effects,
8. cardiac glycosides, e.g. digoxin – risk of heart failure and an increase in plasma cardiac glycosides,
9. with selective serotonin reuptake inhibitors,
10. tacrolimus – risk of toxicity,
11. cyclosporin (increased risk of nephrotoxicity);
12. quinolone antibiotics – the risk of convulsions,
13. oral antidiabetic sulfonylureas – blood glucose levels should be monitored,
14. probenecid and sulfinpyrazone.

Ibuprofen may reduce the anti-aggregating effect of low doses of acetylsalicylic acid, i.e. the inhibition of platelet aggregation.

Mig and side effects

1. The following may occur: indigestion, pain and discomfort in the abdomen, heartburn, nausea, diarrhea, flatulence, constipation, vomiting, gastritis, ulcerative stomatitis, exacerbation of colitis, Crohn’s disease, tarry stools, bloody vomiting, duodenitis, oesophagitis, gastric ulcer and / or duodenal ulcer, gastrointestinal bleeding and perforation (may be fatal, especially in the elderly), liver dysfunction, hepatitis, pancreatitis, jaundice, increased enzyme levels dizziness and headache, depression, insomnia, confusion, mood swings, agitation, drowsiness, irritability and fatigue, seizures, aseptic meningitis with fever or coma, tinnitus, hearing loss, visual disturbances, decreased urine output, renal failure, renal papillary necrosis, increased sodium concentration in os blood eyes (sodium retention), edema, high blood pressure, heart failure.
2. Very rarely, the following may occur: blood and lymphatic system disorders such as: haemolytic and aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia, pancytopenia (the first symptoms of these disorders include: fever, sore throat, superficial ulceration of the oral mucosa, flu-like symptoms, fatigue, bleeding, bruising, ecchymosis, purpura, epistaxis). Exacerbation of inflammations caused by infection (e.g. development of necrotizing fasciitis), which requires immediate medical consultation.
3. The following may occur: hypersensitivity reactions and allergic reactions (rash, itching of the skin, hives, erythema multiforme, swelling of the face, larynx, tongue, dyspnoea, decreased blood pressure, shock, acute shock, exacerbation of asthma, bronchospasm, Stevens-Johnson syndrome, necrosis) toxic spread, alopecia, exfoliative dermatitis, photosensitivity). Isolated cases of symptoms associated with aseptic meningitis (neck stiffness, headache, nausea, vomiting, fever, confusion) have been reported in people with autoimmune diseases (e.g. lupus erythematosus). Long-term use of ibuprofen in high doses (2400 mg daily) may increase the risk of heart attack or stroke.