benefits antivirals (drugs that fight viruses), such as in France aciclovir (Zovirax®) and valaciclovir (Zelitrex®), which are the two antivirals with Marketing Authorization, but also in Canada famciclovir (Famvir®) ) and valaciclovir (Valtrex®), may be prescribed. They are taken orally. They are well tolerated and have few side effects. Antivirals accelerate healing, reduce pain acute and probably limit the onset of post-zone neuralgia if taken within the first 3 days of the rash.

Pain relievers can help relieve pain mild or moderate, in addition to antivirals, such as paracetamol (also called acetaminophen) (Tylenol®, Panadol®, Paracetamol® in Canada, Doliprane®, Daffalgan®, Efferalgan® in France etc.). Pain relievers narcotics, also called opiates, can be prescribed as needed: for example, tramadol or codeine, even morphine (in small doses). 

Remark.  nonsteroidal anti-inflammatory drugs, such as ibuprofen (Advil® in France, Motrin® in Canada, etc.) are not indicated for shingles.

Corticosteroids (such as cortisone) may also be prescribed, but more rarely. In combination with antivirals, they can help reduce (modestly) the duration and intensity of shingles symptoms. However, they do not help prevent post-herpes zoster neuralgia. These drugs are usually reserved for people with very bothersome symptoms, given their side effects.

La post-shingles neuralgia may require, in addition to the use of conventional analgesics, treatment with tricyclic antidepressants, antiepileptics or narcotic analgesics, depending on the severity of the pain. In France, there are also anesthetic patches (Versatis 5% ®) to be applied to the painful area once a day, for a maximum period of 12 hours per 24 hours.