Manti – indications, dosage, contraindications, side effects

Manti is a preparation used in the symptomatic treatment of ailments related to gastric and duodenal ulcer disease, gastritis, hyperacidity, hiatus hernia, indigestion and other gastric disorders.

Manti (US Pharmacia)

SUBSTANCE 1 tablet contains: 0,2 g of aluminum hydroxide, 0,2 g of magnesium hydroxide, 0,025 g of simethicone

ACTION

Manti is a combined antacids preparation used against flatulence.

Manti – indications and dosage

Manti are lozenges recommended:

1. in gastric and duodenal ulcers,
2. in gastritis,
3. in hyperacidity,
4. in the treatment of a hiatal hernia,
5. to treat indigestion and other stomach problems.

Drug dosage

Manti are lozenges that should be taken between meals or in case of ailments. In children, the dosage of the preparation is determined individually. Do not exceed the recommended dose as it may pose a threat to your life or health.

1. Adults. Usually 1-3 tablets. (tablets should be sucked; max. 12 tablets / day)

Manti and contraindications

There are the following contraindications for taking Manti:

1. allergy to any ingredient of the preparation,
2. severe kidney failure,
3. fenyloketonuria,
4. used in parallel with tetracyclines.

Manti – warnings

1. If symptoms persist for more than 2 weeks, consult a doctor.
2. People with renal insufficiency should be careful due to the accumulation of aluminum ions.
3. Long-term dialysis patients are at risk of osteomalacia and risk of encephalopathy.
4. Caution should be exercised in children under 6 years of age, especially those who are dehydrated or with renal insufficiency.
5. Alzheimer’s patients should exercise caution.
6. Taking the drug for too long may cause hypophosphatemia, which is manifested by anorexia, malaise, muscle weakness or bone softening. Kidney failure is also possible.
7. Pregnant and breastfeeding women should consult a doctor before using the preparation.
8. Caution should be exercised in women in the first trimester of pregnancy.
9. Long-term use of Manti is not recommended.

Manti with other drugs

Manti lowers the absorption of tetracycline antibiotics:

1. (e.g. doxycycline) or fluoroquinolones (e.g. ciprofloxacin, norfloxacin),
2. H2 receptor antagonists (used to treat peptic ulcer disease),
3. macrolide antibiotics (azithromycin),
4. protozoal and bactericidal drugs (metronidazole),
5. medicines for high blood pressure (angiotensin converting enzyme inhibitors),
6. beta blockers (atenolol, propranolol),
7. sedatives and hypnotics (benzodiazepine derivatives and phenothiazine neuroleptics),
8. iron preparations,
9. antifungal drugs (ketoconazole),
10. antituberculous (isoniazid),
11. glucocorticosteroids (e.g. cortisol, cortisone, corticosterone),
12. salicylates (e.g. acetylsalicylic acid)
13. drugs used, among others in heart failure and atrial fibrillation (digoxin),
14. medicines for epilepsy (phenytoin)
15. medicines for an underactive thyroid gland (levothyroxine).

Manti can increase the absorption of:

1. oral antidiabetic drugs from the sulfonylurea derivatives group (glipizide, glibenclamide, chlorpropamide, tolbutamide),
2. anticoagulants (coumarin derivatives),
3. some antibiotics (amoxicillin)
4. drugs for ischemic heart disease and high blood pressure (nifedipine),
5. drugs for treating cerebral circulation disorders (pentoxifylline),
6. drugs for rhinitis and sinusitis (pseudoephedrine).

Manti reduces the effectiveness of many drugs used at the same time. These preparations should be administered 2 hours (in the case of fluoroquinolones, more than 4 hours) before or 1-2 hours after taking the drug.

Manti – side effects

Taking Manti may cause the following side effects:

1. constipation
2. diarrhea
3. nausea,
4. vomiting,
5. light color of the stool,
6. kidney failure
7. electrolyte imbalance,
8. increased levels of magnesium, encephalopathy (impaired brain function),
9. bone pain and bone softening (osteomalacia)
10. reducing activity and memory disorders,
11. allergic reactions.