Contents
Maninil is a drug for the treatment of type XNUMX diabetes. The main active ingredient in it is glibenclamide. Maninil is often prescribed to people with diabetes.
At the same time, patients have many questions, which we will answer in this article. For example:
Which dose is more effective – 1.75, 3.5 or 5 mg per day.
What drugs have better efficiency than Maninil.
What to do if the treatment does not help.
Which drug is better: Maninil, Glucophage, Diabeton or Metformin and more.
Instructions for use
Effect | The drug stimulates the production of insulin by pancreatic beta cells, promotes its better absorption in the cells of the body, and reduces the flow of glucose into the blood from the liver. In parallel, the frequency of platelet aggregation decreases, which prevents the formation of blood clots. The drug is rapidly absorbed from the gastrointestinal tract, so it can be taken before meals. Half of the drug is excreted by the kidneys, and the other half by the liver. Maninil does not accumulate in the body. |
When to take | The indication for treatment is type XNUMX diabetes mellitus, which cannot be corrected with diet and physical activity. |
Противопоказания |
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special instructions | If a person develops negative reactions from the side of health, then Maninil should be discontinued. During treatment, it is recommended to refrain from labor and other activities associated with increased concentration. |
dosage | Maninil is taken in the morning and evening before meals. The drug is drunk whole, do not chew. The dosage is selected by the doctor. Release form of the drug: tablets of 1.75, 3.5 and 5 mg. Treatment should begin with taking half a tablet. The average dose is one tablet 2 times a day. Sometimes, but extremely rarely, patients are prescribed 2 tablets 2 times a day. |
Side effects | Adverse events develop most often with incorrect dose selection. So, taking Maninil can lower blood sugar levels and lead to the development of hypoglycemia. This is a dangerous condition that can lead to death. Other side effects include nausea, vomiting, fever, arthralgia, blurred vision, hypersensitivity to sunlight. |
The period of gestation and lactation | Taking medication is not allowed. At this time, only insulin injections can be used. |
Interaction with other drugs | Before taking Maninil with other drugs, you need to consult a specialist. Maninil can react with steroids, ACE inhibitors, beta-blockers, coumarins, pentoxifylline, phenibutazole, reserpine, etc. |
Overdose | When taking an excessive dose of the drug, there is increased sweating, tremor of the limbs, overexcitation, headaches, increased appetite. The person may begin to fall asleep. If the overdose is significant, then a fatal outcome is possible. Therefore, this condition requires essential medical attention. |
Release form, storage features and composition | Release form: tablets of 1.75, 3.5 and 5 mg. The color of the tablets varies from pale pink to pink. Main active ingredient: glibenclamide. Excipients: lactose monohydrate, starch, silicon dioxide, methylhydroxyethylcellulose, magnesium stearate, cochineal red. The drug does not require special storage conditions. The shelf life is 3 years. |
Maninil is produced by the German company Berlin-Chemie AG / Menarini Group. Its price is quite affordable for most people. An analogue of the drug is the drug Glimstrada, which is also produced in Germany.
Inexpensive analogues are produced by Atoll, which is registered in Russia. Although Maninil is also not an expensive drug. Therefore, it is not advisable to replace it with analogues.
The scheme of reception
During the reception, the tablet must be swallowed whole, or broken into 2 parts, but not chewed. It is drunk twice a day – in the morning and in the evening. The dose is selected by the endocrinologist. Self-administration of Maninil is unacceptable, since an incorrect dosage can provoke the development of side effects. After taking the drug, you need to eat so that the blood sugar level does not fall to critical levels.
If Maninil in the dosage prescribed by the doctor has ceased to have the desired effect, then it cannot be increased. You need to contact a doctor. You will most likely need to switch to insulin injections.
What is better Maninil or Diabeton?
Maninil and Diabeton are based on different active ingredients, but they belong to the same group (sulfonylurea derivatives). They reduce blood sugar levels, but with incorrect dose selection, hypoglycemia may develop.
Diabeton acts longer than Maninil. Therefore, it is enough to take it once a day.
What is better Maninil or Glucofage?
Glucophage, unlike Maninil, not only helps to reduce blood sugar levels, but also avoids the development of severe complications of diabetes. However, preference should be given to the original drug, and not to its analogues. You can also pay attention to the drug Glucophage Long.
Is it possible to take Maninil and Metformin in combination?
Combining Maninil and Metformin is not recommended. On the basis of metformin, drugs called Glucofage and Siofor are produced.
How to replace Maninil if it does not work?
If the pancreas has stopped producing insulin, taking Maninil will not have the desired effect. This means that the disease is progressing. If the patient does not go to the doctor and urgently does not begin to receive insulin injections, then he will die from the severe consequences of diabetes mellitus.
Which tablets are stronger than Maninil?
Maninil is a powerful drug for lowering blood sugar levels. If it stops working, then the patient needs insulin injections. No other drugs will help.
Reviews
Patients indicate that Maninil is an affordable drug. Therefore, the choice often falls on him.
You can find reviews regarding the fact that after a few years from the start of taking Maninil ceases to act. However, there are also positive reviews about this drug.