Malupar with an analgesic effect. Suppositories 125, 250 and 500g

Malupar is a preparation used to alleviate pains of various genesis: headaches, toothaches, joint pains and fever. The drug is issued in the form of suppositories and administered rectally. Suppositories contain 125 mg of paracetamol and may enhance the effect of anticoagulants. The preparation used as recommended does not cause psychophysical dysfunction.

Malupar 125, -250, -500 (Aflofarm Fabryka Leków)

Malupar action

Malupar is a non-opioid analgesic and antipyretic drug administered in the form of rectal suppositories.

Malupar indications and dosage of the drug

Malupar is a medicine used to relieve pain:

1. teeth,
2. joints,
3. head,
4. nervous.

Dosage Malupar

The drug is in the form of suppositories and is administered rectally.

Suppositories 125 mg

1. In children over 10 kg – 1 suppository once, not more often than every 4 hours, with a maximum of 4 suppositories a day.
2. Children weighing 25-35 kg – 2 suppositories at a time, not more often than every 4 hours, with a maximum of 8 suppositories a day.

Suppositories 250 mg

1. In children over 10 kg – take 10-15 mk / kg body weight per dose, which can be used no more than 4 times a day. A daily dose of 65 mg / kg body weight should not be exceeded.

Suppositories 500 mg

1. Adults and children after the age of 12: 1 suppository 2-3 times a day.

Ad hoc and analgesic: 1-2 suppositories.

Malupar contraindications for use

Contraindications to the use of Malupar are:

1. allergy to any factor of the drug,
2. liver or kidney failure,
3. viral hepatitis,
4. alcoholism.

Malupar warnings

1. Other paracetamol-containing preparations should not be used concomitantly, due to the risk of overdose.
2. Do not use more than the recommended dose (risk of liver damage).
3. Patients allergic to acetylsalicylic acid derivatives are at risk of developing an allergic reaction.
4. People with hepatic and / or renal insufficiency should exercise caution.
5. People suffering from alcoholism should exercise caution.
6. People who are malnourished, elderly or deficient in glucose-6-phosphate dehydrogenase should also exercise caution.
7. People who regularly starve and consume alcohol are at risk of liver damage while taking the drug.
8. You should not drink alcohol during the treatment.
9. Pregnant and breastfeeding women may take the drug only after consulting a doctor.

Malupar is a sister

1. The paracetamol contained in the drug increases the effect of anticoagulants (coumarin, indanedione), which may cause haemorrhage.
2. Malupar may increase the effects of chloramphenicol.
3. Simultaneous use of salicylamide increases the time of paracetamol excretion.

Not to be combined with:

1. MAOani inhibitors within 14 days from the end of treatment with these preparations due to the possibility of the state of agitation and high temperature,
2. drugs increasing metabolism: rifampicin, antiepileptic drugs (phenytoin, carbamazepine), sleeping pills (barbiturates),
3. alcohol, which can damage the liver
4. non-steroidal anti-inflammatory drugs – kidney damage may occur,
5. phenytoin, which may reduce the effectiveness of the drug and increase the risk of liver problems
6. zidovudine, which is toxic to bone marrow.

Caffeine increases the analgesic effect of paracetamol, and the use of the drug may affect the results of laboratory tests, e.g. blood glucose or uric acid levels.

Malupar and side effects

While taking Malupar, the following may occur (rarely):

1. bad mood,
2. lowering blood pressure,
3. allergic reactions (itching, urticaria, rash, erythema, angioedema),
4. an attack of bronchial asthma,
5. increased heart rate
6. nausea,
7. vomiting,
8. diarrhea,
9. impaired liver and kidney function (up to kidney and liver failure),
10. increased levels of liver transaminases,
11. thrombocytopenia,
12. leukopenia, neutropenia, methaemoglobinaemia (loss of the ability of hemoglobin to transport oxygen).

Very rarely, symptoms of an anaphylactic shock.