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Loperamide is a synthetically produced drug that has a strong anti-diarrheal effect. It is an opioid drug, but it is not a pain reliever. It helps to control the functioning of the intestines and regulates the opioid receptors in the intestinal walls. In this way, Loperamide slows down the peristaltic movements of the intestines.
Loperamide is a drug given during acute diarrhea. They are the result of a disturbed bowel function. As a consequence, bowel movements are more frequent, more abundant and looser in texture than usual. When we suffer from diarrhea, Loperamide can help.
Loperamide – application
The indication for the use of Loperamide is acute and chronic diarrhea. The drug is designed to relieve her symptoms.
Loperamide has also found application in the treatment of patients with ileal fistula. Then its task is to reduce the number of stools and their volume. The drug is also intended to make the stools more compact.
Loperamide can be administered to adults and children after 6 years of age.
Loperamide – composition
The composition of Loperamide includes loperamide hydrochloride. In 1 tablet we find 2 mg of this substance. Among the auxiliary substances there are, among others lactose monohydrate.
Loperamide – contraindications
Contraindication to the use of Loperamide is hypersensitivity to any substance contained in the drug. It cannot be given to children under the age of 6.
Loperamide cannot be used in people:
- patients with dysentery, which causes blood in the stool, and patients with fever;
- with an acute relapse of ulcerative colitis;
- patients with bacterial enterocolitis caused by Salmonella, Shigella and Campylobacter bacteria;
- patients with pseudomembranous enteritis treated with broad-spectrum antibiotics.
A general contraindication to the administration of Loperamide is any case in which intestines should not be slowed down. The risk of complications is then very high. Discontinue use if constipation, flatulence or intestinal obstruction occur while using the drug.
It should also be remembered that Loperamide only reduces symptoms. If the cause of the diarrhea can be identified, it should be treated.
Loperamide should not be used during pregnancy and breastfeeding.
Loperamide – side effects
Most often, any side effects caused by Loperamide are related to the symptoms of diarrhea. This includes abdominal pain and discomfort, nausea and vomiting, dry mouth, and constipation and flatulence. In addition, general fatigue, drowsiness and dizziness may appear.
It is very rare that a rash, itching or hives appear after taking Loperamide. Sometimes Stevens-Johnson syndrome or toxic epidermal necrolysis may appear. Urinary retention and varying degrees of severity of allergic reactions and even anaphylactic shock may also occur.
Loperamide – dosage
Loperamide can be administered to adults and children over 6 years of age. Depending on the situation, the following are given:
- acute diarrhea – at the beginning 2 tablets – adults or 1 tablet of children, then 1 tablet after each loose stool;
- chronic diarrhea – at the beginning 2 tablets – adults and 1 tablet – children a day. The dose should be changed until the stools return to normal.
A maximum of 8 tablets can be given, i.e. 16 mg daily for adults. For children, the daily dose is 3 tablets per 20 kg of body weight per day.
Loperamide – precautions
Diarrhea is associated with a loss of fluid and electrolytes and can quickly lead to dehydration. It is especially dangerous for children. Therefore, the most important thing is to properly hydrate the body and replenish electrolytes.
Loperamide should not be used continuously. If diarrhea is not resolved after 48 hours, stop taking it and see your doctor.
People with liver problems should use Loperamide with caution as it is easy for them to overdose. People with AIDS should stop taking the drug when the first symptoms of flatulence appear. The presence of lactose in Loperamide means that it should not be used in people with hereditary galactose intolerance, glucose-galactose malabsorption and Lapp lactase deficiency.
Loperamide – dinner
You have to pay from 30 to 4 PLN for a package of Loperamide containing 8 tablets.
Before use, read the leaflet, which contains indications, contraindications, data on side effects and dosage as well as information on the use of the medicinal product, or consult your doctor or pharmacist, as each drug used improperly is a threat to your life or health.