• Hospitalization is essential if it is a visceral form. In fact, without treatment, the visceral form proves to be fatal in a few months.The drug treatment includes antiparasitic drugs derived from antimony such as Glucantime (N-methyl-glucamine) or Pentostam (stibiogluconate), by intramuscular injection (painful ).
• The treatment depends on the form of leishmaniasis (cutaneous, mucous membrane or visceral), the extent of the lesions and the parasitic species involved.
• The route of administration of the drug depends on the form: local and general for the cutaneous form, systemically for the visceral and mucous membrane.

Drug treatment includes antiparasitic drugs derived from antimony such as Glucantime (N-methyl-glucamine) or Pentostam (stibiogluconate), by intramuscular injection (painful). Pentacarinat (pentamidine isethionate), certain antifungals (against fungi), such as fluconazole, ketoconazole or amphotericin B, and Impavido (miltefosine) are also used. Finally, treatment with gamma interferon combined with an antimony derivative appears to be effective in certain forms of leishmaniasis.