Lactulosum Polfarmex for constipation and liver failure. What is the dosage of the drug?

Lactulosum is a drug used in gastroenterology and family medicine for the symptomatic treatment of constipation and liver failure. The preparation acts on the gastrointestinal tract, has a slight laxative effect and reduces the absorption of ammonia into the blood. Lactulosum is available as a syrup and is dispensed without a prescription.

Lactulosum Polfarmex (Polfarmex)

form, dose, packaging availability category the active substance
syrup 0,5 g/ml (7,5 g/15 ml) (150 ml) OTC (over-the-counter) lactulose

Indications for the use of Lactulosum

The active substance of the preparation is lactulose – an osmotic laxative. Lactulosum is administered in chronic constipation, acute liver failure (with pre-coma and pre-coma) and in chronic liver failure with increased blood ammonia levels.

Dosage of Lactulosum:

  1. chronic constipation;
  2. adults: 30-45 ml before breakfast or 15 ml three times a day before meals, then after achieving the effect of 3 ml on an empty stomach;
  3. children: it is recommended to administer after diluting the syrup with water or juice;
  4. initially in infants 2,5 ml / d,
  5. in children up to the age of 3 5 ml / d,
  6. in children after 3 years of age 15 ml / d, then the dose may be increased every 3 days until normal bowel movements are obtained.
  7. acute and chronic liver failure: adults 100-180 ml / d in 4-6 divided doses.
  1. adults: 30-45 ml before breakfast or 15 ml three times a day before meals, then after achieving the effect of 3 ml on an empty stomach;
  2. children: it is recommended to administer after diluting the syrup with water or juice;
  3. initially in infants 2,5 ml / d,
  4. in children up to the age of 3 5 ml / d,
  5. in children after 3 years of age 15 ml / d, then the dose may be increased every 3 days until normal bowel movements are obtained.
  1. initially in infants 2,5 ml / d,
  2. in children up to the age of 3 5 ml / d,
  3. in children after 3 years of age 15 ml / d, then the dose may be increased every 3 days until normal bowel movements are obtained.

Lactulosum and contraindications and warnings

Contraindications to the use of Lactulosum are: intestinal obstruction, galactosemia, hypersensitivity to any component of the preparation.

Lactulosum – warnings

  1. If constipation does not improve after a few days of using the preparation, a doctor should be consulted.
  2. Long-term use of the preparation in high doses may lead to diarrhea and disturbances in water and electrolyte balance; then blood levels of sodium, potassium and chloride should be monitored (especially in elderly patients).
  3. Before using Lactulosum during pregnancy or breastfeeding, consult your doctor.

Lactulosum with other medications

Since lactulose lowers the pH of the large intestine (the contents of the large intestine become acidic), it may reduce the effect of drugs whose release depends on the pH of the colon.

Lactulosum – side effects

The following may occur: transient flatulence (especially in the initial period of using the preparation), abdominal pain, nausea, vomiting.

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