Are ibuprofen and paracetamol combinations safe?
Are ibuprofen and paracetamol combinations safe?
The combination of ibuprofen and paracetamol is safe, of course, taking into account all individual contraindications to the use of each of these drugs as monotherapy (one drug separately). The different mechanism of action of ibuprofen and paracetamol enables the combined administration of these two active substances both in two independent forms of drugs (e.g. tablets) or in one preparation, in accordance with the principles of combining analgesics. Combining ibuprofen with paracetamol can produce an effective analgesic effect in mild to moderate pain with the use of lower doses of the individual components. In other words, for an effective analgesic effect, we must use a higher dose of ibuprofen and paracetamol separately (monotherapy) compared to the doses of these drugs used simultaneously. This also applies to its antipyretic effect. Despite the combination of ibuprofen and paracetamol, the results of clinical trials do not indicate the addition of side effects. In order to keep the treatment safe, however, we should check what painkillers we use, because there are many drugs on the market with various trade names containing both paracetamol and ibuprofen. There is therefore a real risk of, in a sense, unknowingly exceeding the allowable doses when the same active substance is used under different trade names.
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