Intensive training permanently changes human metabolism

High-intensity interval training (HIIT) permanently affects human skeletal muscles, increasing the amount of important proteins necessary for energy metabolism and muscle contraction, reports the Polish Press Agency after the scientific journal “eLife”.

  1. HIIT training (High Intensity Interval Training) consists in alternating the pace of the exercises
  2. Very fast pace of e.g. running, cycling, squats is maintained for 15 seconds and returns to a moderate exercise pace
  3.  HITT was developed with athletes preparing for the competition in mind
  4. Currently, it is used by people who want to quickly get rid of unnecessary fat
  5. The training takes about 25-30 minutes
  6. More current information can be found on the Onet homepage.

HIIT training permanently changes human metabolism

This study (https://dx.doi.org/10.7554/eLife.69802) helps explain the beneficial effects of HIIT training on human metabolism, emphasize its authors from the University of Copenhagen (Denmark).

“Exercise brings many benefits to the body, including prevent metabolic diseases, and if they do develop, they help with treatment. This is probably the result of changes in the energy consumption of skeletal muscles that occur thanks to interval training “- explains Prof. Morten Hostrup, lead author of the publication.

The rest of the article below the video material.

Together with his team, the professor decided to test how HIIT-type exercises modulate the protein content in skeletal muscles and how they regulate the activity of these proteins through a chemical reaction called acetylation.

Acetylation is the substitution of a hydrogen atom in the molecule of an organic compound by an acetyl group. In the case of proteins, this reaction can lead to a change in their activity.

For the experiment, researchers recruited eight healthy men who had never practiced sports professionally. The participants’ task was to complete a five-week intensive cycling training. The men exercised three times a week in the HIIT system: four minutes of cycling at the maximum possible intensity (90% of maximum heart rate), followed by a two-minute rest. They repeated this pattern four to five times in one training unit.

Using a technique called mass spectrometry, scientists analyzed the changes in the composition of 3168 proteins isolated from tissue samples taken from the participants’ thighs before and after the experiment. They also examined changes related to lysine acetylation in the analyzed proteins.

Do you exercise intensively? Try a gel for massage of joints and muscles after intense workouts. You can find it in Medonet Market. To support muscle regeneration after training, reach for Aqua Kick Pear Power for quick regeneration after training OstroVit – a dietary supplement in the form of an easily dissolving powder.

HIIT increases protein production

It turned out that as a result of HIIT training, there was a significant increase in the production of proteins used to build mitochondria, i.e. cell energy centers, and proteins related to muscle contractions. Increased acetylation of mitochondrial proteins and enzymes involved in the production of cellular energy has also been noted. In addition, researchers observed a change in the amount of proteins that reduce the calcium sensitivity of skeletal muscles, a sensitivity that is essential for muscle contraction.

As the authors emphasize, such results not only confirm some well-known phenomena that take place in skeletal muscle proteins as a result of regular exercise, but also identify new ones.

  1. In order to provide the body with more proteins, it is worth starting additional supplementation with the use of protein supplements for athletes. We recommend, among others: HMB (beta-hydroxy beta-calcium methylbutyrate) OstroVit powder. If you want to lose unnecessary kilograms faster, you can start using OstroVit Fat Burner eXtreme or OstroVit Fat Burner for women. You can also reach for the Shot Fat Burner, which is convenient to use and can be taken with you, for example, for training.

“Using the latest proteomic technology, we provided new insight into how skeletal muscles adapt to exercise training. We identified completely new mechanisms by which exercise modifies proteins in muscle cells and described the sites of their acetylation, the researchers conclude. “We hope our work will stimulate further research into how exercise helps improve human metabolic health.” (PAP)

author: Katarzyna Czechowicz

cap / ekr /

We encourage you to listen to the latest episode of the RESET podcast. This time we devote it to self-compassion – a trend that has developed very strongly in the United States, but is still in its infancy in Poland. What is it and how does it affect our daily functioning? You will hear about this and many other issues related to self-compassion in the latest episode of our podcast.

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