Ibuprofen does not make COVID-19 more severe. The Danes refuted the hypothesis from the beginning of the pandemic
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The use of non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen or diclofenac, is not associated with any adverse effects in people infected with the SARS-CoV-2 virus, researchers from the University of Southern Denmark showed.

In the early phase of the COVID-19 pandemic, there were concerns that the use of the painkiller ibuprofen could lead to a more severe course of coronavirus disease. Since the use of this agent, as well as other NSAIDs, is common, there was an urgent need to obtain accurate data on their safety.

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The team of dr. Anton Pottegard collected data on all 9326 residents of Denmark who tested positive for SARS-CoV-27 between February 29 and April 2020, 2. Data included information on NSAID use, hospitalization, mortality, mechanical ventilation, and renal replacement therapy. It found that 248 patients (or 2,7%) had their prescription for NSAIDs within 30 days of receiving a positive test for the virus.

Scientists have found no relationship between any aspect of the course of the infection and the use of NSAIDs. Among the participants using the funds from this group, 6,3 percent. died, 24,5 percent were hospitalized, and 4,9 percent intensive care units were admitted.

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Meanwhile, among infected people who were not treated with NSAIDs, 6,1%, 21,2% died. were hospitalized, and 4,7 percent. admitted to intensive care. Thus, these differences are statistically insignificant.

“Given the evidence available, there is no reason to avoid NSAIDs during the SARS-CoV-2 pandemic,” the authors conclude. – However, account should always be taken of other well-established side effects of NSAIDs, especially their effects on the kidneys, digestive system and cardiovascular system. NSAIDs should be used at the lowest dose possible for the shortest possible time in all patients. ‘

Find out more:

  1. Facts and myths about ibuprofen
  2. Ibuprofen aggravates the course of COVID-19 disease?
  3. Ibuprofen tested for COVID-19 treatment? It alleviates the symptoms of coronavirus

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