Used in rheumatic and muscle pain, back pain, neuralgia, pain and swelling due to post-exercise damage (sprains, strains). Also in pain in osteoarthritis.
Ibufen (Medana)
| form, dose, packaging | availability category | the active substance |
| gel 0,1 g / g (10%) (50 g) | OTC (over-the-counter) | ibuprofen (ibuprofen) |
ACTION
Non-steroidal anti-inflammatory drug
INDICATIONS AND DOSAGE
Rheumatic and muscular pains, back pain, neuralgia. Pain and swelling due to stress injuries (sprains, strains). Also in pain in osteoarthritis. Up to 3 times a day, apply a 3-cm strip of gel to the aching area of the joints and periarticular tissues and gently massage into the skin.
CONTRAINDICATIONS
Hypersensitivity to any component of the preparation, allergic skin diseases, infectious diseases with skin lesions, skin damage and burns. Do not use in patients with asthma who have a history of attacks of breathlessness, rash and rhinitis or other allergic symptoms after taking acetylsalicylic acid or other non-steroidal anti-inflammatory drugs. Do not use in children up to 12 years of age.
WARNINGS
Use with caution in people with renal failure, peptic ulcer disease, cardiovascular failure or liver dysfunction. People with bronchial asthma or symptoms of allergic reactions after taking acetylsalicylic acid, as well as taking other medications (especially drugs that lower blood pressure, diuretics, cardiac and psychotropic drugs) with gastrointestinal complaints or kidney diseases, and people who have not taken acetylsalicylic acid before or other non-steroidal anti-inflammatory drugs should contact your doctor. The eyes and mucous membranes should be protected against contact with the preparation. In the event of skin lesions at the site of application, treatment should be discontinued. Do not use more often than every 4 hours and not more than 3 times a day. Wash hands after use; it is recommended to use gloves when massaging the gel into the skin for a long time. If the symptoms do not improve or worsen after 2 weeks of using the drug, contact your doctor. Pregnant and breastfeeding women may use the preparation only on the recommendation of a doctor and only if absolutely necessary. There are no data on the effect of the preparation on the ability to drive motor vehicles.
INTERACTIONS
There are no known interactions of ibuprofen applied topically with other drugs, however, effects similar to oral administration cannot be excluded. Do not use simultaneously with acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (increased risk of gastrointestinal side effects), antihypertensive drugs and diuretics (non-steroidal anti-inflammatory drugs may reduce the effectiveness of these drugs), anticoagulants (non-steroidal anti-inflammatory drugs may increase the effect of anti-inflammatory drugs). blood clotting [e.g. warfarin] or thrombolytic factors [e.g. streptokinase]), lithium and methotrexate (NSAIDs can increase plasma levels of both lithium and methotrexate), zidovudine (bleeding time may be prolonged in patients treated concomitantly with ibuprofen and zidovudine). Ibuprofen may irreversibly cancel the platelet aggregation inhibition effect caused by acetylsalicylic acid intake, limiting the protective effect of this drug on the heart in patients at high risk. Concomitant administration of corticosteroids and non-steroidal anti-inflammatory drugs may increase the risk of gastrointestinal ulcer disease.
SIDE EFFECTS
The following may occur: reddening and tingling of the skin, rash, itching, hives, angioedema, epidermal necrolysis and erythema multiforme, gastrointestinal discomfort, abdominal pain, non-specific allergic and anaphylactic reactions; Respiratory reactions manifested by asthma, worsening of asthma, bronchospasm or shortness of breath. During long-term use on large surfaces, possible: thrombocytopenia, agranulocytosis, headache and dizziness, nausea, recurrence of gastric ulcer or gastric bleeding, kidney damage.