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More than a year has passed since COVID-19 challenged humanity. The enemy turned out to be much more insidious than we expected: a stronger immune response is required to counteract new mutations of the virus.
A new seasonal wave of influenza and SARS is expected this fall. Therefore, now we need to pay special attention to enhanced immunity support. We have reviewed the latest research3, 5-7, 10, 11 and prepared recommendations that will help enhance the effect of vaccination or revaccination and not get sick again.
Let’s spur the antibodies!
If you have not been sick with COVID-19 or have already suffered an infection and are now preparing for a vaccination or revaccination, use our tips to help increase its effect.
Give up alcohol… Experts strongly recommend that you stop drinking alcohol 3 days before vaccination and not drink it for at least 3-5 days after it.
Replenish Vitamin D Deficiency… According to the chief freelance nutritionist of the Ministry of Health of Russia, scientific director of the Federal Research Center for Nutrition, Biotechnology and Food Safety, Academician of the Russian Academy of Sciences Viktor Tutelyan, after vaccination, attention should be paid to replenishing the vitamin D3 deficiency1which promotes the production of antibodies2.
“The effectiveness of vitamin therapy depends on the correct dosages. For example, the average prophylactic daily dose of vitamin D3 during the COVID-19 pandemic, according to American recommendations, is 1000-3000 IU, vitamin C – 1000 mg3… Zinc is recommended to be taken in a dosage of 25-50 mg per day.3, and folate – 600 mcg4… The Evalar company produces a wide range of vitamins and minerals not only in the form of complexes, but also monopreparations. They can be taken independently or included in existing dosage regimens, choosing the required dosage and the most convenient form of release for you, ”notes Ekaterina Stenina, an expert in nutritional science at Evalar CJSC.
Consume more protein… This is another recommendation from Academician Victor Tutelyan.1 Proteins are needed to “build” antibodies, which are protein structures. In addition to foods rich in proteins (meat, fish, eggs, etc.), delicious protein shakes will come to the rescue. And vegetarians should lean on plant proteins. An excellent solution can be, for example, spirulina, especially since it is rich not only in protein, but also in vitamins and minerals to support immunity.
Avoid foods that exacerbate allergies… People prone to allergies should avoid chocolate, smoked meats, strawberries, citrus fruits, blue cheeses, and other foods that can aggravate an allergic reaction.
Don’t sit on antihistamines, if you are not allergic… One recent study showed that prophylactic use of these drugs slows down the immune response to the vaccine.
Our top 7 virus defenders
And now we will talk about drugs for maintaining immunity, as well as the health of the respiratory system and blood vessels. This is very important, because they become targets not only for the new coronavirus, but also for long-familiar respiratory viruses, such as influenza.
Multivitamins
An expert group from the European Food Safety Authority (EFSA) has identified ten nutrients that are essential for the immune system to function. These include six vitamins – D, C, A, B6, folate and B12, as well as four minerals – zinc, iron, copper and selenium.7 Many of these components also have antiviral properties. Zinc, for example, inhibits the multiplication of coronaviruses in the body, and selenium has been found to be able to prevent viral mutations.5, 6.
It is one of the most famous regulators of the immune response, promoting the production of antibodies.5,6 and antiviral proteins of interferons. Also vitamin C has anti-inflammatory properties7 and helps fight oxidative stress5that contributes to the development of at least 100 different diseases, including acquired immunodeficiency8.
“The Evalar company produces a wide range of vitamins and minerals with high dosages of active ingredients. They are developed taking into account international experience and modern recommendations. At the same time, we choose the most active forms of delivery of vitamins, minerals and other components to the body to increase their bioavailability and maximum absorption: effervescent tablets for vitamins and minerals, tablets for resorption (for example, with vitamin D3), micellar form for curcumin, etc. . ”, – explains Ekaterina Stenina, an expert in the field of nutrition of JSC“ Evalar ”.
Back in January 2021, a group of scientists from leading Irish universities sent a letter to the government with a recommendation to include vitamin D intake in the list of COVID-19 prevention measures.9which enhances the immune response10… In a recent foreign study, it was shown that patients with a more severe course of COVID-19 had lower levels of the “sun” vitamin than with a mild form of infection.10.
Adequate zinc content in the body plays an important role in ensuring an adequate immune response. Interestingly, in the course of systemic biological analysis, 118 zinc-containing proteins associated with antiviral protection were isolated, and 11 of them are directly related to protection against single-stranded RNA viruses (these include the causative agent COVID-19).11 Scientists note the ability of zinc to inhibit the RNA polymerase enzyme of coronaviruses and thus suppress their spread in the body.5,6.
It is a unique natural bioregulator – Siberian larch bioflavonoid, a reference antioxidant and vascular protector. As you know, one of the striking features of COVID-19 is vascular damage and increased thrombus formation. Dihydroquercetin strengthens the walls of blood vessels and capillaries, protecting them from damage, improves microcirculation and prevents blood clots12, 13… In addition, it helps to maintain normal functions of the bronchopulmonary system: the tone of the bronchial wall, normal bronchial patency and indicators of external respiration.14
Also, dihydroquercetin has an immunomodulatory effect, stimulates the production of interferons12, 13.
Black elderberry is an effective plant stimulant of the immune system. Research has shown that when it is used, the duration of flu symptoms is reduced to 3-4 days. In addition, people who took elderberry showed higher levels of antibodies to the influenza virus.15… Black elderberry exhibits immunomodulatory, anti-inflammatory, antioxidant and antiviral properties16… This suggests the potential efficacy of elderberry not only for influenza, but also for other viral infections.
This is what gives the famous Indian spice turmeric its signature golden color! But for us, curcumin is a real find! It turns out that in our body it has an unprecedented number of target molecules. Curcumin Shows Immunomodulatory Properties17helping to protect against viruses, bacteria and fungi18, has anti-inflammatory and antioxidant activity19.
Multivitamins
Be sure to try our … In it you will find all 10 vitamins and minerals that we have listed in the article. The tablet provides a gradual release of the components, which guarantees their maximum absorption.20
And for fans of effervescent vitamins, we suggest evaluating Multivitamins A to Zn Evalar in an easily accessible21 effervescent tablet form. Each of them contains 11 vitamins + 7 minerals + folate. And as a bonus for you – the bright citrus taste of the finished drink.
Vitamin C
The assortment of “Evalar” contains vitamin C in various dosages and forms of release. Check out the benefits of some of them.
Wide range of dosages: 2000 mg (maximum22), 1200 mg, 1000 mg, 900 mg or 250 mg per tablet.
Readily available21 effervescent form.
No preservatives or gluten.
Strong citrus taste.
, и Vitamin C 100 mg Calcium Ascorbate Tablets
They contain vitamin C in a non-acidic form of ascorbate, which is absorbed faster and remains active longer.23
Suitable for patients with gastrointestinal problems.
Safe for the stomach.23
Vitamin D3
“The power of the sun” in every drop … What are we talking about? Of course oh Vitamin D3 500 ME from “Evalar”! In our opinion, it is an excellent solution for replenishing the need for “solar” vitamin in adults and children from 3 years old.24
– this is:
100% natural24 easily digestible vitamin D3 in coconut oil;
convenient dosage: 5000 IU in 10 drops;
neutral taste and smell;
no alcohol;
economical consumption of the drug (360 doses in 1 bottle of 10 ml);
high quality raw materials (BASF SE, Germany).
Zinc
The company “Evalar” produces two monopreparations of zinc with a high25 dosage of a trace element – 25 mg.
Only26 zinc preparation in readily available amino acid chelated form, which ensures maximum assimilation of the mineral.27
Allowed for pregnant and lactating women.27,28
Economical packaging – 100 tablets.
Readily available21 effervescent form.
Free from gluten, colorings and preservatives.
Allowed for vegetarians.
The drink will delight you with the pleasant taste of mango.
dihydroquercetin
The drug will help to reveal all the properties of a unique natural bioregulator from the Evalar company.
It contains high 29 dosage of pure dihydroquercetin obtained from Siberian larch raw material – 25 mg in each tablet.
Elder
To help your immune system function at full strength during the respiratory infection season, take , the properties of which are complemented and strengthened by vitamins C, E and zinc.
Gummy-berry chewable lozenges with a rich blackcurrant flavor are both healthy and tasty to fuel your immune system.
curcumin
Unfortunately, the curcumin in the spice is very poorly absorbed. Therefore, if you want to fully unleash the natural power of this substance, take curcumin in an easily digestible30 micellar form or curcumin in combination with piperine. This active ingredient in black pepper enhances the bioavailability of curcumin.31
By the way, there are such drugs in the assortment of the Evalar company. You can choose micellar or Curcumin with Evalar piperine.
Take advantage of our recommendations, because now the immune system needs especially active support!
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1 Electronic resource: https://tass.ru/moskva/10494837 (date of access: 28.06.2021).
2 Terrie Y.C. The Important Role of Vitamin D // Pharmacy Times, February 2010 Infectious Disease, Volume 76, Issue 2.
3 COVID-19 Management Protocol. An overview of the MATH+ and I-MASK+ Protocols. Developed and Updated by Paul Marik, MD, FCP (SA), FRCP (C), FCCP, FCCM. Professor of Medicine, Chief of Pulmonary and Critical Care Medicine Eastern Virginia Medical School. December 27th, 2020.
4 Gromova O.A., Limanova O.A., Torshin I.Yu., Kerimkulova N.V., Rudakov K.V. Dose-dependence of the protective effects of folic acid in the pregravid period, during pregnancy and during lactation // BC. 2014. No. 1. P. 37–34.
5 Calder P.C. Nutrition and immunity: lessons for COVID-19 // Eur J Clin Nutr (2021). https://doi.org/10.1038/s41430-021-00949-8.
6 Calder PC. Nutrition, immunity and COVID-19 // BMJ Nutrition, Prevention & Health 2020; 0. doi: 10.1136/bmjnph-2020-000085.
7 Galmés S., Serra F., Palou A. Current State of Evidence: Influence of Nutritional and Nutrigenetic Factors on Immunity in the COVID-19 Pandemic Framework // Nutrients 2020, 12, 2738; doi: 10.3390/nu12092738.
8 Balabolkin M.I., Klebanova E.M. The role of oxidative stress in the pathogenesis of vascular complications of diabetes (lecture) // Problems of endocrinology. 2000. T. 46. No. 6. P. 29–34.
9 Electronic resource: https://www.independent.ie/irish-news/irish-expertsback-role-of-vitamin-d-to-prevent-virus-40006152.html (date of access: 12.07.2021).
10 Alipio M. Vitamin D Supplementation could possibly improve clinical outcomes of patients infected with Coronavirus-2019 (COVID-19). SSRN Electron J. 2020. doi: 10.2139/ssrn.3571484.
11 Gromova O.A. Torshin I.Yu. The importance of zinc for maintaining the activity of innate antiviral immunity proteins: an analysis of publications on COVID-19. Preventive medicine. 2020; 23 (3): 131-139.
12 Dihydroquercetin and arabinogalactan – natural bioregulators in human and animal life, use in agriculture and food industry / Yu.P. Fomichev et al. M .: “Scientific Library”, 2017. – 702 p.
13 Leontyeva N.V. Dihydroquercetin – Natural Antioxidant: A Study Guide. SPb: North-Western State Medical University named after I. I.I. Mechnikova, 2016 p.
14 Electronic resource: https://www.vidal.ru/drugs/molecule/1793 (date of access: 06.07.2021).
15 Barak V. et al. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines // Eur Cytokine Netw. Apr-Jun 2001; 12 (2): 290-296.
16 Fitseva N.S., Lukashov R.I. Antioxidant properties of hydroalcoholic extracts from black elderberry flowers (Sambucus Nigra Flos). Fundamental Science in Modern Medicine-2020. Minsk: BSMU; 340-344.
17 Catanzaro М., Corsini Е., Rosini М., Racchi М., Lanni С. Immunomodulators Inspired by Nature: A Review on Curcumin and Echinacea // Molecules. 2018 Nov; 23 (11): 2778. doi: 10.3390/molecules23112778.
18 Moghadamtousi S.Z., Kadir H.A., Hassandarvish P., Tajik H., Abubakar S., Zandi K. A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin // BioMed Research International. Volume 2014. Article ID 186864. http://dx.doi.org/10.1155/2014/186864.
19 Gupta S.C, Patchva S., Aggarwal B.B. Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials // The AAPS Journal. 2013. Vol. 15. No. 1. Р. 195–218. doi: 10.1208/s12248-012-9432-8
20 Confirmed by SoGR No. KZ.16.01.98.003.E.000716.08.19 dated 23.08.2019.
21 Shevchenko A.M. Features of the production of instant dosage forms. Medical business, 2005; 2-3.
22 In the assortment of CJSC “Evalar”.
23 Confirmed by SoGR No. AM.01.07.01.003.R.000359.11.20 from 20.11.2020, AM 01.07.01.003.R.000087.03.21 from 04.03.2021, AM.01.07.01.003.R.000046.02.21 from 09.02.2021.
24 Confirmed by SoGR No. AM.01.07.01.003.R.000116.11.19 dated 15.11.2019
25 Corresponds to 167% of the adequate daily intake, but does not exceed the upper acceptable level.
26 In the assortment of ZAO “Evalar” among preparations containing zinc.
27 Confirmed by SoGR No. KZ.16.01.98.003.E.000043.01.20 dated 20.01.2020.
28 As prescribed by a doctor.
29 100% of an adequate daily intake.
30 Confirmed by SoGR No. KZ.16.01.98.003.E.000908.09.16 dated 15.09.2016.
31 Martini N. Turmeric // J Prim Health Care 2019; 11 (2): 187–188.
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