Hitaxa – characteristics, action and dosage of the drug for allergies

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Hitaxa is a prescription antiallergy medicine. It comes in the form of an oral solution or orodispersible tablets. The active substance is desloratadine. Can anyone use Hitaxa? How to properly dose this preparation? What are the side effects of Hitaxa? How much does Hitax cost and can this drug be reimbursed?

Hitaxa (Adamed) – drug characteristics

Hitaxa is an antiallergic drug issued on prescription. It is a preparation available in several variants that differ in form and content of the active substance. In pharmacies you can buy:

1. oral solution 0,5 mg / ml in bottles of 60 and 150 ml;
2. 2,5 mg orodispersible tablets in packs of 10 and 30 pieces;
3. 5 mg orodispersible tablets in packs of 10 and 30.

Hitaxa can also be purchased without a prescription, in the following variants:

1. Hitaxa fast 5 mg in packs of 10;
2. Hitaxa fast junior 2,5 mg in packs of 10 pieces.

The manufacturer of the drug Hitaxa is a family-owned pharmaceutical and biotechnology company with 100% Polish capital. The Adamed company was founded in 1986 and currently has about 500 products, offered to patients in 75 countries around the world.

Which Polish pharmaceutical companies convince Poles the most? Check: Customer satisfaction from Polish pharmaceutical companies: which is the most convincing?

Hitaxa – composition and action of the drug

Properties of the drug Hitaxa are associated with the presence of the active ingredient – desloratadine. Due to the presence of desloratadine, the preparation belongs to the group of second-generation antihistamines.

It works by selectively blocking peripheral type 1 histamine receptors, thus preventing allergy-specific symptoms. Desloratadine is practically devoid of sedative effects as it is non-CNS depleting.

Desloratadine is a compound that is the main active metabolite of loratadine. Both of these compounds are histamine antagonists and selectively block peripheral type 1 histamine receptors. Thus, peripherally the histamine which is responsible for allergic symptoms is inhibited peripherally.

To understand the mechanism of action of drugs containing Desloratadine, it is necessary to understand the action of histamine itself. Histamine is an amine that occurs naturally in our body. This amine is involved in the formation of inflammatory processes. It is called an inflammatory mediator. Histamine is produced, among others, by in the lungs, nasal and stomach mucosa and skin.

Histamine works by stimulating histamine receptors, which leads to contraction of smooth muscles, including bronchitis or increase the permeability of venous vessels. The consequences of this action are swelling, blisters or other skin changes, itching and pain.

It is worth mentioning that vitro desloratadine inhibits the release of cytokines by human mast cells and basophils. These mechanisms are believed to be responsible for reducing the allergic reaction.

Desloratadine relieves symptoms of allergies, including: sneezing, runny nose, watery and red eyes, swelling and itching of the mucous membranes, and hives.

In addition to desloratadine, Hitaxa also contains excipients, including: potassium polyacryline, citric acid monohydrate, red iron oxide (E 172), magnesium stearate, croscarmellose sodium, Tutti Frutti flavor, liquid (also contains propylene glycol), aspartame (E 951) , microcrystalline cellulose, mannitol (spray-dried), potassium hydroxide (for pH adjustment).

What is allergy manifested? Check: Allergens – types of allergens, allergy symptoms

Desloratadine – absorption and metabolism

Desloratadine is a compound that is well absorbed after oral administration. Its maximum concentration in the blood is achieved approximately 3 hours after taking the drug.

It is difficult to talk about the metabolism of this compound because the enzyme responsible for the metabolism of desloratadine has not yet been known. Therefore, an interaction of Hitaxa with other medicinal preparations cannot be ruled out. The effect of desloratadine after administration lasts longer than 24 hours, on average about 27 hours.

How is an e-visit to an allergist? Check: Allergy under control. How to prepare for an e-visit to an allergist?

Hitaxa – indications for the use of the drug

Hitaxa is a drug intended to relieve allergic symptoms:

1. hives;
2. allergic rhinitis.

Most of the side effects of Hitaxa are mild and temporary.

What is chronic rhinitis and how to treat it? Check: Chronic rhinitis and its types

Hitaxa – dosage

Dosage of Hitaxa depends on the form of the preparation. In any case, follow the doctor’s instructions and do not exceed the specified dose. The dosage information is also provided in the package leaflet.

Orodispersible tablets:

1. adults and adolescents after 12 years of age: 5 mg once a day;
2. children 6-11 years of age: 2,5 mg in one daily dose.

Oral solution:

1. adults and adolescents over 12 years of age: 10 ml in one daily dose;
2. children 6-11 years of age: 5 ml once a day;
3. children aged 1-5 years: 2,5 ml in one daily dose.

It is worth remembering that when treating periodic rhinitis, taking the drug should be discontinued after the symptoms disappear and resumed when they reappear. However, in the case of chronic allergic rhinitis, the doctor may decide to use the drug continuously throughout the period of the allergen.

Hitaxa can be taken with or without food. The tablet disintegrates in the mouth and there is no need to take it with water or any other liquid.

If a dose is missed, the patient should take the missed dose as soon as possible. The treatment regimen should then be continued. If it is almost time for your next dose, do not make up for the missed dose by taking double the amount of Aerius.

What is worth remembering for the drugs we use to be effective? Check: How to take medications effectively?

Hitaxa – contraindications to use

In the case of Hitaxa, the leaflet informs about the following contraindications:

1. hypersensitivity to any component of the preparation;
2. the period of pregnancy and breastfeeding;
3. age below 1 year of age – in the case of the oral solution;
4. age below 6 years – in the case of tablets.

Due to the presence of aspartame (a source of phenylalanine), the drug cannot be taken by people suffering from phenylketonuria.

What diagnostics is necessary if an allergy is suspected? Check: Controlled sensitization, i.e. what tests should be performed for allergy?

Hitax – warnings

Warnings for taking Hitaxa:

1. the recommended dose should not be exceeded;
2. caution should be exercised when driving vehicles or operating machinery, as the preparation may cause drowsiness in some people;
3. caution should be exercised in people with severe renal insufficiency;
4. caution should be exercised if the preparation is used in people who have ever had seizures or had seizures in another family member, as well as in young children, due to their greater susceptibility to seizures while taking desloratadine

If in doubt, consult your doctor.

How not to confuse allergies with flu or coronavirus? Check: Allergy, Flu or Coronavirus? Symptoms can be confusing

Hitaxa – drug interactions

If you are taking Hitaxa, inform your doctor about other medications you are taking. As the enzyme responsible for the metabolism of desloratadine (the active substance) has not been identified, an interaction with other preparations cannot be ruled out.

It has been found that the concomitant use of Hitaxa with ketoconazole or erythromycin does not cause any clinically significant interactions.

Hitaxa and pregnancy, breastfeeding and fertility

Always consult your doctor about taking medications during pregnancy or breastfeeding. Animal studies have shown that desloratadine is not teratogenic. However, the safety of this medicine for use in pregnancy has not been established. Which is why Taking Hitaxa is not recommended during pregnancy.

Desloratadine is a compound excreted into breast milk, therefore the use of Hitaxa during lactation is also not recommended.

So far, there have been insufficient studies on the effect of the preparation on fertility.

What is worth remembering when taking medication during pregnancy? Read: Pregnancy and medications

Hitaxa – side effects

Some side effects may occur during treatment with Hitaxa, but not all people will experience them.

Side effects include:

1. somnolence;
2. tiredness;
3. dizziness;
4. nausea and vomiting;
5. headaches;
6. dry mouth;
7. breathing difficulties;
8. stomach pain;
9. wheezing;
10. tachycardia;
11. itch;
12. hives and swelling;
13. palpitations;
14. anaphylactic shock.

Side effects of unknown frequency also include: unusual behavior, aggressive behavior, changes in the way the heart beats, photosensitivity, weight gain or increased appetite.

In the case of the drug in the form of an oral solution, in clinical trials conducted in children aged 6-23 months. side effects such as fever, insomnia, diarrhea.

What medications should not be given to children? Check: Warning, these drugs can be dangerous to children

How much does Hitax cost?

The price of the drug Hitaxa it depends on the chosen variant of the preparation and the pharmacy in which we obtain the drug. By averaging the prices for the drug Hitaxa, we will pay:

1. orodispersible tablets; 2,5 mg; 10 tablets – about 8 zlotys;
2. orodispersible tablets; 2,5 mg; 30 tablets – about PLN 10, after a refund of about PLN 5;
3. orodispersible tablets; 5 mg; 10 tablets – about 10 zlotys;
4. orodispersible tablets; 5 mg; 30 tablets – about PLN 20, after a refund of about PLN 10
5. oral solution; 0,5 mg / ml; 150 ml – about PLN 20, after a refund of about PLN 10;
6. oral solution; 0,5 mg / ml; 60 ml – about PLN 13.

How to reduce the amount of allergens at home? Read on: Allergy’s home – ways to reduce allergens at home

Hitaxa – similar drugs

Hitaxa is not the only drug available that contains desloratadine. Other preparations with this active substance are:

1. Aerius – oral solution or coated tablets;
2. Alerdes – oral solution or coated tablets;
3. AlergoTeva – coated tablets; 
4. Aleric Deslo Active – oral solution or orodispersible tablets;
5. Dasselta – coated tablets;
6. Delortan – oral solution or coated tablets;
7. Deslodyna – oral solution or coated tablets;
8. Desloratadine Aurovitas – oral solution or coated tablets;
9. Dynid – oral solution or tablets;
10. Goldesin alerstop – coated tablets);
11. Jovesto – oral solution or coated tablets;
12. Laboratories PolfaŁódź ALERGO MAX – coated tablets;
13. Laboratories PolfaŁódź ALERGO MAX JUNIOR – oral solution;
14. Teslor – oral solution or coated tablets.

How to choose the most effective allergy medications? Check: How to choose allergy pills? Popular and effective drugs

Before use, read the leaflet, which contains indications, contraindications, data on side effects and dosage as well as information on the use of the medicinal product, or consult your doctor or pharmacist, as each drug used improperly is a threat to your life or health. Do you need a medical consultation or an e-prescription? Go to halodoctor.pl, where you will get online help – quickly, safely and without leaving your home. Now you can use e-consultation also free of charge under the National Health Fund.