Etopiryna Control

Etopyrin Kontrol is a drug used for moderate pain (e.g. headache, muscle or joint pain), fever in the course of a cold, viral infections, etc. n The preparation is available without a prescription and is in the form of tablets. Due to the caffeine content, the drug has a greater analgesic effect and moderately stimulates the central nervous system.

Etopiryna Control (Polpharma)

SUBSTANCE 1 tablet contains: 0,3 g of acetylsalicylic acid, 0,05 g of caffeine

Control Etopyrin – action

Etopyrin Kontrol is a preparation with an analgesic, anti-inflammatory and antipyretic mechanism. Etopyrine contains: salicylates, including acetylsalicylic acid and etenzamide, and caffeine. The latter – caffeine, increases the analgesic effect of salicylates. The preparation has a slight stimulating effect on the central nervous system.

Etopyrin Control indications and drug dosage

Etopyrin Kontrol is a drug designed to relieve mild pain:

1. Headache,
2. muscle pain,
3. arthralgia,
4. pains accompanying fever during colds and viruses.

The preparation is in the form of tablets and should be taken orally (preferably with a meal, washed down with water). Etopyrin Kontrol should be used in accordance with its intended use and medical recommendation, as exceeding the daily dose may endanger your life or health.

Dosage of the drug:

1. Adults and children after 12 years 1-2 tablets 3 × / d; maximum daily dose. 4 g of acetylsalicylic acid.
2. Children 12-16. more than 3 tablets a day.

Contraindications to the use of Etopyrin Kontrol

When should you not use Etopyrin Kontrol?

1. You are hypersensitive to any of the ingredients of the drug or to other anti-inflammatory drugs.
2. You suffer from bronchial asthma.
3. You suffer from chronic respiratory diseases.
4. You have a sleep fever.
5. You develop nasal swelling.
6. You have stomach and duodenal ulcers.
7. You have bleeding and inflammation in your digestive tract.
8. You have severe liver, kidney or heart failure.
9. You have a blood clotting disorder.
10. You are using other anticoagulants in parallel.
11. You are deficient in glucose-6-phosphate dehydrogenase.
12. You are also taking methotrexate at a dose of 15 mg / week. or more.
13. You are under 12 years old.
14. You are pregnant and breastfeeding.

Control Etopyrin – warnings

1. Symptomatic treatment without medical advice can be carried out for no more than 3 days.
2. Do not use in patients with impaired renal function and chronic renal or hepatic failure.
3. Caution should be exercised in patients with impaired liver or kidney function.
4. Caution should be exercised when using the preparation in patients with juvenile rheumatoid arthritis and / or systemic lupus and with liver failure, as the toxicity of salicylates increases, liver function should be monitored.
5. Use with caution in women with vaginal bleeding, with excessive menstrual bleeding and using contraceptive intrauterine devices.
6. It is contraindicated to use the drug in patients with hypertension, heart failure, psychomotor agitation, suffering from insomnia.
7. Caution should be exercised when using methotrexate in doses lower than 15 mg / week, due to the increased toxicity of methotrexate on the bone marrow. Concomitant use with methotrexate in doses greater than 15 mg / week is contraindicated.
8. Caution should be exercised in people taking oral antidiabetic and anti-gout agents; there is a risk of an increase in the blood glucose-lowering hypoglycaemic effect.
9. The preparation should be discontinued 5-7 days before the planned surgery due to the risk of prolonged bleeding time both during and after surgery.
10. Alcohol should be consumed during treatment with Etopyrin, due to the increased risk of damage to the gastrointestinal mucosa.
11. The preparation belongs to the group of drugs that may adversely affect female fertility due to the possession of a substance belonging to the group of non-steroidal anti-inflammatory drugs. This effect is transient and disappears after the end of therapy.
12. In elderly patients, use in lower doses and at greater intervals in time, due to the increased risk of side effects in this group of patients.

Control Etopyrin with Other Drugs

Etopyrin Kontrol may be used with the following drugs and foodstuffs only after consulting a doctor:

1. Use with ACE inhibitors (e.g. enalapril, captopril) may reduce the effect of antihypertensive drugs.
2. Concurrent use with acetazolamide may increase its toxicity.
3. Valproic acid (acetylsalicylic acid enhances the toxic effect of valproic acid, and valproic acid enhances the anti-aggregating effect of acetylsalicylic acid).
4. Use with diuretics may reduce their effectiveness and the ototoxicity of furosemide may occur.
5. The use of the drug with methotrexate may increase its toxicity to the bone marrow.
6. Taking non-steroidal anti-inflammatory drugs (e.g. ibuprofen) increases the risk of side effects in the digestive tract.
7. Systemic corticosteroids (with the exception of hydrocortisone used as replacement therapy in Addison’s disease) increase the risk of peptic ulcer disease and gastrointestinal bleeding, and reduce plasma salicylate levels during treatment and, after treatment, increase the risk of salicylate overdose.
8. Taking antidiabetic drugs may increase the hypoglycaemic effect by reducing the blood glucose levels of these drugs.
9. Preparations increasing the excretion of uric acid (e.g. probenecid, sulfinpyrazone) reduce the effect of these drugs; digoxin (an increase in its effect may occur).
10. Thrombolytic (blood clot-dissolving) drugs such as streptokinase and alteplase (potentiation of its effect may occur).
11. Barbiturany (np. phenobarbital).
12. Taking oral contraceptives; cimetidines and disulfirams; ergotamines and analeptics (e.g. nicetamide).
13. Concomitant consumption of alcohol can cause gastrointestinal bleeding.
14. Omeprazole and ascorbic acid (vitamin C) do not affect the absorption of acetylsalicylic acid.
15. Do not use with methotrexate in doses of 15 mg per week or more, or with anticoagulants (heparin, coumarin derivatives).

Control Etopyrin – side effects

1. The following may occur: indigestion, heartburn, epigastric fullness, nausea, vomiting, anorexia, abdominal pain, gastrointestinal bleeding, damage to the gastric mucosa, activation of ulcer disease, perforation (gastric ulceration occurs in 15% of patients on long-term acetylsalicylic acid treatment) , focal hepatic cell necrosis, liver tenderness and enlargement, especially in patients with juvenile rheumatoid arthritis, systemic lupus erythematosus, rheumatic fever or liver disease; transient increases in serum transaminases, alkaline phosphatase and bilirubin levels;
2. The following may occur: tinnitus (usually after an overdose), hearing disturbances, dizziness, visual disturbances, hand tremors, insomnia; proteinuria, urine leukocytes and red blood cells, papillary necrosis, interstitial nephritis, cardiac disorders, heart failure, hypertension, non-cardiac pulmonary edema; thrombocytopenia (reduction in the number of platelets in the blood), anemia due to gastrointestinal microhaemorrhages, haemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency, leukopenia (reduction in the number of leukocytes in the blood), agranulocytosis (lack of granulocytes in the blood), eosinopenia (reduction in the number of eosinophils blood), increased risk of bleeding, increase in bleeding time and / or increase in prothrombin time.
3. Possible hypersensitivity reactions: rash, urticaria, angioedema (swelling of the face, tongue and trachea), bronchospasm, shock.