Erdomed – indications, contraindications, dosage and price

Proven content

Erdomed is a prescription drug used in diseases of the lungs, bronchi and upper respiratory tract. This preparation can be purchased in the form of tablets and a powder for oral suspension. Erdomed has an expectorant effect, and its use helps to get rid of secretions in the respiratory tract. What is the composition of the preparation and when is it worth reaching for? Are there any contraindications to the use of this drug? How to dose Erdomed correctly and what to remember when using it?

Erdomed – general characteristics of the drug

Erdomed is a preparation that is available in pharmacies with a prescription issued by a doctor. It is a drug that is used to treat diseases that affect the lungs, bronchi and upper respiratory tract. Two forms of Erdomed are available in pharmacies – capsules and powder for oral suspension. Patients are also offered an over-the-counter preparation. It is Erdomed Muko, which has an effect similar to that of a prescription drug.

Erdomed package contains 20 capsules, in aluminum / PVC blisters in a cardboard box. The pack of Erdomed powder for oral suspension contains 50 g of the preparation.

The manufacturer of the drug is Aziende Chimiche Riunite Angelini Francesco, while the entity responsible for the distribution of the preparation in Poland is Angelini Pharma Polska. Angelini is an Italian company with 100 years of experience in the production and distribution of medicinal products. Angelini Pharma has been present on the Polish market since 1995.

The company deals mainly with the production and distribution of drugs, medical devices and dietary supplements focused on ailments such as pain, depression, osteoarticular diseases, female diseases, oncology and inflammations of the mouth and throat. The most famous and popular among Polish patients are such preparations as Tantum Verde, Tantum Rosa, Magvit B6 or Visolvit Junior.

What is an e-prescription and how is it issued? Read: How does issuing an e-prescription look like during a TV visit? [WE EXPLAIN]

Erdomed – composition and action of the drug

Erdomed is a mucolytic drug, i.e. it liquefies and reduces the viscosity of the mucus in the respiratory tract. The active substance of this preparation is erdosteina.

Erdosteine ​​is a derivative of the methionine amino acid. It is a secretolytic drug from the group of mucolytics. This drug is used in situations of excessive production and accumulation of sticky mucus in the airways.

In a healthy organism, secretions protect the respiratory tract by preventing the mucosa from drying out and by enabling the cilia of the respiratory epithelium to function. However, in disease, when there is excessive production of secretions, the movement of the cilia is impaired. As a result of impaired functioning of the cilia, the secretion becomes too thick and sticky, and it begins to linger in the respiratory tract. It is only possible to choke it if it is thinned and liquefied.

Erdostein liquefies the secretion in the respiratory tract by changing its composition. This drug may reduce the content and structure of mucoproteins in the secretion of the respiratory tract, reduce its surface tension, and also cause its enzymatic degradation.

Erdosteine ​​consists of two blocked sulfhydryl groups. These groups are released during metabolism in the liver. The resulting metabolites break down mucus glycoproteins into smaller molecules, thereby liquefying the secretion, reducing its viscosity and improving its transport outside the human body. Thanks to these processes, mucus production is increased, the patient can cough up the mucus more easily, and the function of the respiratory epithelium improves. Erdostein in therapeutic doses does not have a significant effect on the gastrointestinal mucosa.

Erdosteine ​​also acts as an antioxidant by neutralizing free radicals. This substance increases the concentration of amoxicillin in bronchial secretions.

The action of erdostein it additionally strengthens the proper hydration of the patient, as well as the treatment with kinesitherapy, i.e. patting and proper positioning of the patient.

The excipients of Endored capsules are:

1. powidon;
2. microcrystalline cellulose;
3. magnesium stearate;
4. gelatine;
5. titanium dioxide;
6. yellow iron oxide;
7. indigotine.

In turn, the auxiliary substances of the powder preparation are:

1. sucrose;
2. benzoesan soda;
3. sodium carboxymethyl starch;
4. citric acid anhydrous;
5. sucralose;
6. 1201973 – Mask CLD nat. pwd flavor (vanillin, natural flavoring substances, sodium starch octenyl succinate, vegetable (coconut) oil, silicon dioxide, alpha – tocopherol)
7. 1204571 – 1115061 blood orange pwd flavor (orange oil, maltodextrin (corn), gum arabic, butylated hydroxyanisole (BHA), flavors, natural flavors).

How is the respiratory system built and what diseases most often affect it? Read: Everything you need to know about the respiratory system

Erdomed – indications for use

Erdomed capsules can be given to patients from 12 years of age. The powder version of the drug can be used in the treatment of respiratory diseases in children over 2 years of age.

The indications for the use of the drug Erdomed are:

1. diseases of the lungs, bronchi and upper respiratory tract of acute and chronic course, accompanied by abnormal secretion and difficult transport of secretions, inflammation of the sinuses, nose, trachea, larynx, bronchi or lungs;
2. prophylaxis of seasonal aggravation of the course of chronic bronchitis.

How to recognize and treat bronchitis? Check: Bronchitis – symptoms, types, treatment, complications [EXPLAINED]

Erdomed – contraindications

Despite its effectiveness in the treatment of respiratory diseases, Erdomed cannot be used by every patient struggling with secretion.

Contraindications to the use of the drug Erdomed are:

1. hypersensitivity to erdostein or any other component of the preparation or any substance containing free SH groups;
2. renal failure with a CCr less than 25 ml / min;
3. liver problems, such as increased liver enzymes;
4. homocystynuria;
5. phenylketonuria – the restriction applies to the powdered drug as it contains aspartame;
6. age of the patient – in the case of the drug in capsules, the drug should not be used in children under 12 years of age, and in the case of the oral suspension in children under 2 years of age. 

What is a wet cough and what can it mean? Check: Wet cough

Erdomed – precautions

Before and during the use of Erdomed, follow the precautions included in the package leaflet.

Precautions to be followed are:

1. in the event of hypersensitivity symptoms such as rash or urticaria, discontinue treatment immediately and contact your doctor;
2. due to the risk of accumulation of large amounts of mucus, the drug should be used with caution in patients with weakened cough reflex or impaired ciliary clearance;
3. you should not take medications that inhibit the cough reflex (antitussive drugs, e.g. codeine) at the same time, because this reflex promotes the removal of a large amount of secretion formed after liquefaction;
4. Erdomed Muko contains sucrose (3,5 g in 1 sachet), therefore people with diabetes should pay attention to it, while patients with intolerance to certain sugars should consult a doctor before using them;
5. the risk of side effects can be reduced by taking the lowest effective dose;
6. no dose adjustments are required for adult patients with chronic obstructive pulmonary disease (COPD);
7. in patients with severe renal insufficiency, erdostein metabolites formed in the liver may accumulate;
8. no dosage adjustment is necessary in patients over 65 years of age.

How to recognize and treat chronic obstructive pulmonary disease? Check: Chronic obstructive pulmonary disease

Erdomed – drug storage

The method of its storage is very important for the effectiveness and stability of the drug. Keep Erdomed out of the sight and reach of children.

The temperature of the place where the medicine will be stored should not exceed 25 degrees Celsius.

In the case of powdered medicine, the reconstituted suspension should be stored in a refrigerator at 2 ° C to 8 ° C, but not longer than 15 days. The preparation should always be shaken before use, as the suspension may delaminate during storage in a refrigerator

It should also be remembered that the preparation cannot be used after the expiry date shown on the package. Expired medications must not be disposed of via wastewater or household waste. Special containers for expired drugs are usually available at pharmacies. You can also ask your pharmacist for advice on the disposal of expired medicines.

What should I do with out-of-date medications? Check: Returning drugs to the pharmacy? We check what the regulations say

Erdomed – correct dosage

The correct dosage of Erdomed should always be determined by the prescribing physician. The dosage is also described in the package leaflet.

Dosage of Erdomed depends on the variant of the preparation used by the patient.

Erdomed capsules are for oral use and can be taken with or without food. The appropriate dose for adults and children over 12 years of age is 1 capsule twice a day. The drug should not be used immediately before going to bed.

Erdomed powder is administered orally after preparation of the solution. The solution is prepared by adding water to the powder bottle at room temperature. An appropriate indentation is marked on the bottle to inform the patient about the required amount of water. The mixture should be shaken until the powder and water form a thin cloudy suspension. In this way, 100 ml of ready-to-use suspension are obtained. The prepared suspension should be stored in a refrigerator at 2-8 ° C, but not longer than 10 days.

In the case of children over 2 years of age, the appropriate dosage of the drug is determined by the doctor. The dose is adjusted according to the child’s weight, usually 10 mg per kilogram body weight, divided into 2 doses.

Dosage of Erdomed in children is described as follows:

1. body weight 15-20 kg: 2,5 ml twice a day;
2. body weight 21-30 kg: 5 ml twice a day;
3. body weight over 30 kg: 7,5 ml twice a day.

How to take medication correctly? Check: How to take medications effectively?

Erdomed – side effects

Like all Erdomed medicinal products, it can cause side effects in patients, but these may not be experienced by every person using this medicine. After authorization of the medicinal product, it is important to report any suspected adverse reactions so that the benefit / risk balance of the medicinal product can be monitored.

The general classification of the frequency of adverse body reactions (ADRs) is based on the following principles: very common (≥1 / 10), common (≥1 / 100 to <1/10), uncommon (≥1 / 1 to <000/1), rare ( ≥100 / 1 to <10 / 000), very rare (<1 / 1), not known (cannot be estimated from the available data).

The following side effects are indicated with Erdomed:

1. Common side effects (affects 1 to 10 patients in 100) – stomach discomfort, nausea, headache;
2. Uncommon side effects (affects 1 to 10 patients in 1000) – heartburn, constipation, diarrhea, dry mouth, dizziness, generally feeling unwell;
3. Rare side effects (affects 1 to 10 users in 10) – no sensation or altered taste, rash, hives, fever.

What is drug allergy and how do you recognize it? Check: Drugs are also allergenic

Erdomed and pregnancy and breastfeeding

The use of drugs during pregnancy should always be consulted with the attending physician. So far, no detailed studies have been conducted that would unequivocally define the safety of Erdomed in pregnant women.

Similarly, there is insufficient information on the transfer of Erdomed into human milk, therefore the use of the product by women during breast-feeding is not recommended.

What dietary supplements should you use before pregnancy? Check: Supplementation before pregnancy. What vitamins to take when planning a pregnancy?

Erdomed – interactions with other drugs

Before taking Erdomed, tell your doctor about all prescription, over-the-counter, and herbal remedies you are taking.

The studies and analyzes performed so far have not shown any interaction of Erdomed with other drugs that are used in the treatment of respiratory tract infections.

However, combination therapy with antitussive drugs may cause a patient to build up a large amount of bronchial secretions. This state of affairs may lead to a deterioration of the patient’s condition, e.g. due to a deterioration of the respiratory efficiency. To avoid complications, you should not take antitussive and secretolytic drugs at the same time, especially at bedtime.

It is also worth remembering that the parallel use of Erdomed and amoxicillin increases the concentration of amoxicillin in the respiratory tract.

What interactions are there between popular drugs? Check: Dangerous interactions

Erdomed — cena

The price of the drug Erdomed may differ depending on the town where the preparation will be purchased or the selected pharmacy. The amount you will have to pay for the preparation also depends on the size of the purchased package and the selected drug variant.

A package with 10 capsules of the Erdomed drug costs about PLN 13-15, while 20 capsules of the drug cost about PLN 23-25. 50 g of powder, from which you can make 100 ml of suspension, costs about PLN 20. The Erdomed Muko packaging, in which there are 20 sachets, costs about PLN 30.